J 2007

Acute and repeated exposure to methamphetamine changes expression of CB1 receptor in mesencephalon of the mouse brain

LANDA, Leoš and Michal JURAJDA

Basic information

Original name

Acute and repeated exposure to methamphetamine changes expression of CB1 receptor in mesencephalon of the mouse brain

Name in Czech

Akutní a opakovaná expozice metamfetaminu mění expresi CB1 receptoru v mesencefalonu myšího mozku

Authors

Edition

European Neuropsychopharmacology, Amsterdam, Elsevier, 2007, 0924-977X

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Austria

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 4.430

Organization unit

Faculty of Medicine

UT WoS

000251231901273

Keywords in English

PCR; behavioural sensitization; methamphetamine; cannabinoids; CB1 receptor; mesencephalon

Tags

Tags

International impact, Reviewed
Changed: 19/6/2009 14:20, MUDr. Michal Jurajda, Ph.D.

Abstract

ORIG CZ

In the original language

Real-time PCR results showed increased CB1 mRNA expression after both methamphetamine and methanandamide first doses followed by decrease in CB1 mRNA expression observed after the challenge dose of methamphetamine, i.e. in sensitized animals.

In Czech

Výsledky real time PCR ukázaly zvýšenou expresi mRNA CB1 jak po první dávce metamfetaminu tak metanandamidu a následně snížení exprese mRNA CB1, která bylo pozorováno po provokující dávce metamfetaminu, tzn. u senzitizovaných zvířat.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.