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@article{746028,
author = {Kizek, René and Adam, Vojtěch and Mikelová, Radka and Jaromír, Hubálek and Pavel, Hanustiak and Miroslava, Beklova and Petr, Hodek and Ales, Horna and Libuše, Trnková and Marie, Stiborová and Ladislav, Zeman and Křížková, Soňa},
article_number = {10},
doi = {http://dx.doi.org/10.3390/s7102402},
keywords = {flavonoids; antioxidant; carbon paste electrode; square wave voltammetry},
language = {eng},
issn = {1424-8220},
journal = {Sensors},
title = {Utilizing of square wave voltammetry to detect flavonoids in the presence of human urine},
volume = {7},
year = {2007}
}
TY - JOUR
ID - 746028
AU - Kizek, René - Adam, Vojtěch - Mikelová, Radka - Jaromír, Hubálek - Pavel, Hanustiak - Miroslava, Beklova - Petr, Hodek - Ales, Horna - Libuše, Trnková - Marie, Stiborová - Ladislav, Zeman - Křížková, Soňa
PY - 2007
TI - Utilizing of square wave voltammetry to detect flavonoids in the presence of human urine
JF - Sensors
VL - 7
IS - 10
SP - 2402-2418
EP - 2402-2418
SN - 14248220
KW - flavonoids
KW - antioxidant
KW - carbon paste electrode
KW - square wave voltammetry
N2 - About biological affecting of flavonoids on animal organisms is known less, thus we selected flavonoids, flavanones and flavones, and their glycosides, which were examined as potential inducers of cytochrome(s) P450 when administrated by gavages into experimental male rats. The study was focused on induction of CYP1A1, the major cytochrome P450 involved in carcinogen activation. The data obtained demonstrate the necessity of taking into account not only ability of flavonoids to bind to Ah receptor (induction factor) but also to concentrate on their distribution and metabolism (including colon microflora) in the body. After that we examined certain flavonoids as potential inducers of cytochrome P450, we wanted to suggest and optimize suitable electrochemical technique for determination of selected flavonoids (quercetin, quercitrin, rutin, chrysin and diosmin) in body liquids. For these purposes, we selected square wave voltammetry using carbon paste electrode.
ER -
KIZEK, René, Vojtěch ADAM, Radka MIKELOVÁ, Hubálek JAROMÍR, Hanustiak PAVEL, Beklova MIROSLAVA, Hodek PETR, Horna ALES, Trnková LIBUŠE, Stiborová MARIE and Zeman LADISLAV. Utilizing of square wave voltammetry to detect flavonoids in the presence of human urine. \textit{Sensors}. 2007, vol.~7, No~10, p.~2402-2418. ISSN~1424-8220. Available from: https://dx.doi.org/10.3390/s7102402.
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