| HORNA, Aleš, Ondřej ZÍTKA, Soňa KŘÍŽKOVÁ, Vojtěch ADAM, Libuše TRNKOVÁ, Miroslava BEKLOVÁ a René KIZEK. Investigation of cisplatin-glutathione-DNA interactions. In EuroMedlab Amsterdam 2007. Amsterdam, The Netherlands: International Federation of Clinical Chemistry and Laboratory Medicine, 2007, s. 348-348. ISSN 1437-8523. |
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@inproceedings{746851,
author = {Horna, Aleš and Zítka, Ondřej and Křížková, Soňa and Adam, Vojtěch and Trnková, Libuše and Beklová, Miroslava and Kizek, René},
address = {Amsterdam, The Netherlands},
booktitle = {EuroMedlab Amsterdam 2007},
keywords = {Sulfhydryl group; glutathion; electrochemical measurement},
language = {eng},
location = {Amsterdam, The Netherlands},
pages = {348-348},
publisher = {International Federation of Clinical Chemistry and Laboratory Medicine},
title = {Investigation of cisplatin-glutathione-DNA interactions},
year = {2007}
}
TY - JOUR
ID - 746851
AU - Horna, Aleš - Zítka, Ondřej - Křížková, Soňa - Adam, Vojtěch - Trnková, Libuše - Beklová, Miroslava - Kizek, René
PY - 2007
TI - Investigation of cisplatin-glutathione-DNA interactions
PB - International Federation of Clinical Chemistry and Laboratory Medicine
CY - Amsterdam, The Netherlands
KW - Sulfhydryl group
KW - glutathion
KW - electrochemical measurement
N2 - Sulfhydryl group of glutathione is highly reactive and is often found conjugated to other molecules such as nitric oxide via its sulfhydryl moiety. Thus it is not a surprise that GSH can even influence a treatment of diseases including cancer. In malignant tumours, as compared with normal tissues, the multidrug resistance associates in most cases with higher GSH levels within these cancer cells. Stationary electrochemical measurements were carried out the AUTOLAB Analyser. Coulochem III coupled with flow injection analysis was used as flow electrochemical instrument.
ER -
HORNA, Aleš, Ondřej ZÍTKA, Soňa KŘÍŽKOVÁ, Vojtěch ADAM, Libuše TRNKOVÁ, Miroslava BEKLOVÁ a René KIZEK. Investigation of cisplatin-glutathione-DNA interactions. In \textit{EuroMedlab Amsterdam 2007}. Amsterdam, The Netherlands: International Federation of Clinical Chemistry and Laboratory Medicine, 2007, s.~348-348. ISSN~1437-8523.
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