ŠVESTKA, Jaromír, Oldřich SYNEK a Jana TOMANOVÁ. Differences in the effect of second-generation antipsychotics on prolactinaemia: Six weeks open-label trial in female in-patients. Neuroendocrinology Letters. Sweden, Stockholm: Maghira and Maas Publications, 2007, roč. 28, č. 6, s. 881-888. ISSN 0172-780X.
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Základní údaje
Originální název Differences in the effect of second-generation antipsychotics on prolactinaemia: Six weeks open-label trial in female in-patients
Název česky Rozdílnost efektu antipsychotik druhé generace na prolaktinémii. Šestitýdenní otevřená studie u pacientů ženského pohlaví
Název anglicky Differences in the effect of second-generation antipsychotics on prolactinaemia: Six weeks open-label trial in female in-patients
Autoři ŠVESTKA, Jaromír, Oldřich SYNEK a Jana TOMANOVÁ.
Vydání Neuroendocrinology Letters, Sweden, Stockholm, Maghira and Maas Publications, 2007, 0172-780X.
Další údaje
Originální jazyk čeština
Typ výsledku Článek v odborném periodiku
Obor 30000 3. Medical and Health Sciences
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 1.443
Organizační jednotka Lékařská fakulta
UT WoS 000252066300027
Klíčová slova anglicky second-generation antipsychotics; hyperprolactinaemia; prevalence; dynamics of change; correlations with other parameters
Štítky correlations with other parameters, dynamics of change, hyperprolactinaemia, prevalence, second-generation antipsychotics
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: prof. MUDr. Eva Češková, CSc., učo 726. Změněno: 30. 6. 2009 09:54.
Anotace
The main objective was to evaluate the effect of five second-generation antipsychotics (amisulpride, quetiapine, olanzapine, risperidone, and zotepine) on prolactinaemia during 6 week therapy in 433 female in-patients with mainly schizophrenic disorders. Secondary objectives included identification of dynamics of change in serum prolactin levels and correlations of changes of prolactinaemia with some demographic and clinical parameters. The trial was a prospective, open-label, single-center one with a flexible dosing of SGAs. The therapeutic effect of SGAs was assessed by a change of scores of CGI-S and CGI-I scales from a baseline to the endpoint. Blood samples were taken in the morning under fasting condition.
Anotace anglicky
The main objective was to evaluate the effect of five second-generation antipsychotics (amisulpride, quetiapine, olanzapine, risperidone, and zotepine) on prolactinaemia during 6 week therapy in 433 female in-patients with mainly schizophrenic disorders. Secondary objectives included identification of dynamics of change in serum prolactin levels and correlations of changes of prolactinaemia with some demographic and clinical parameters. The trial was a prospective, open-label, single-center one with a flexible dosing of SGAs. The therapeutic effect of SGAs was assessed by a change of scores of CGI-S and CGI-I scales from a baseline to the endpoint. Blood samples were taken in the morning under fasting condition.
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