Detailed Information on Publication Record
2007
Heterogeneity of mantle cell lymphoma
MAČÁK, Jirka, Jana ŠMARDOVÁ, Iva KROUPOVÁ, Barbora RAVČUKOVÁ, Martin KLABUSAY et. al.Basic information
Original name
Heterogeneity of mantle cell lymphoma
Name in Czech
Heterogenita lymfomu z buněk plášťové zóny
Name (in English)
Heterogeneity of mantle cell lymphoma
Authors
MAČÁK, Jirka, Jana ŠMARDOVÁ, Iva KROUPOVÁ, Barbora RAVČUKOVÁ, Martin KLABUSAY and Leoš KŘEN
Edition
Virchows Archiv, Německo, Springer Verlag, 2007, 0945-6317
Other information
Language
Czech
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.029
Organization unit
Faculty of Medicine
UT WoS
000249454600976
Keywords in English
mantle cell lymphoma; immunohistochemistry; molecular biology
Změněno: 22/1/2008 07:01, prof. MUDr. Jirka Mačák, CSc.
Abstract
V originále
Results show that MCL was uniform in morphology and in type of infiltration, which was in all cases diffuse. Very useful marker for diagnosis seems to be hyaline deposits scattered in the lymphoma tissue. Number of mitoses enable us include 6 cases to the blastoid variant of MCL. In immunohistochemistry, CD5 and cyclinD-1 markers were negative in 30 % of cases. Mutation of p53 gene is rare in MCL. In our series were found two cases with mutation of gene p53.