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@proceedings{748402,
author = {Jíra, Miroslav and Závodná, Eva and Honzíková, Nataša and Nováková, Zuzana and Vašků, Anna and Izakovičová Hollá, Lydie and Fišer, Bohumil},
keywords = {baroreflex sensitivity; angiotenzin II type 1 receptor; polymorphism; spectral analysis},
language = {eng},
title = {Baroreflex Sensitivity And A1166C Polymorphism In AT1 Receptor Gene},
year = {2007}
}
TY - CONF
ID - 748402
AU - Jíra, Miroslav - Závodná, Eva - Honzíková, Nataša - Nováková, Zuzana - Vašků, Anna - Izakovičová Hollá, Lydie - Fišer, Bohumil
PY - 2007
TI - Baroreflex Sensitivity And A1166C Polymorphism In AT1 Receptor Gene
KW - baroreflex sensitivity
KW - angiotenzin II type 1 receptor
KW - polymorphism
KW - spectral analysis
N2 - Decreased baroreflex sensitivity (BRS in ms/mmHg; BRSf in mHz/mmHg) contributes to the development of hypertension and to the risk of sudden cardiac death in patients after myocardial infarction. The aim of this study was to evaluate association of single nucleotide polymorphism A1166C in angiotensin II type 1 receptor (AT1R) gene with BRS and BRSf in man. We found significant association of A1166C polymorphism in AT1 receptor gene with baroreflex sensitivity. Less frequent allele was associated with decreased BRS and BRSf.
ER -
JÍRA, Miroslav, Eva ZÁVODNÁ, Nataša HONZÍKOVÁ, Zuzana NOVÁKOVÁ, Anna VAŠKŮ, Lydie IZAKOVIČOVÁ HOLLÁ a Bohumil FIŠER. \textit{Baroreflex Sensitivity And A1166C Polymorphism In AT1 Receptor Gene}. 2007.
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