Detailed Information on Publication Record
2008
Brain metabolism and diffusion in the rat cerebral cortex during pilocarpine-induced status epilepticus
ŠLAIS, Karel, Ivan VOŘÍŠEK, Norbert ZOREMBA, Aleš HOMOLA, Lesia DMYTRENKO et. al.Basic information
Original name
Brain metabolism and diffusion in the rat cerebral cortex during pilocarpine-induced status epilepticus
Name in Czech
Difúze a metabolizmus v mozkové kůře potkana v průběhu pilokarpinem indukovaného epileptickáho záchvatu
Authors
ŠLAIS, Karel (203 Czech Republic, guarantor), Ivan VOŘÍŠEK (203 Czech Republic), Norbert ZOREMBA (276 Germany), Aleš HOMOLA (203 Czech Republic), Lesia DMYTRENKO (804 Ukraine) and Eva SYKOVÁ (203 Czech Republic)
Edition
Experimental Neurology, United States, Academic Press, 2008, 0014-4886
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30104 Pharmacology and pharmacy
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 3.974
RIV identification code
RIV/00216224:14110/08:00025693
Organization unit
Faculty of Medicine
UT WoS
000252500900020
Keywords in English
Diffusion; ADCW; Microdialysis; Pilocarpine; Epilepsy; Glucose; Glutamate; Pyruvate; Lactate; Potassium
Tags
Tags
International impact, Reviewed
Změněno: 23/6/2009 09:21, MUDr. Mgr. Karel Šlais, Ph.D.
V originále
The real-time iontophoretic method using tetramethylammonium-selective microelectrodes and diffusion-weighted magnetic resonance imaging were used to measure the extracellular space volume fraction, tortuosity and apparent diffusion coefficient of water (ADCW) 240 min after the administration of pilocarpine in urethane-anaesthetized rats. The obtained data were correlated with extracellular lactate, glucose, and glutamate concentrations and the lactate/pyruvate-ratio, determined by intracerebral microdialysis.
In Czech
Práce studovala změny difúzních parametrů v kortexu mozku potkana při epileptickém záchvatu navozeném pilokarpinem. Dále byly sledovány extracelulární koncentrace laktátu, glutamátu, glukózy a pyruvátu a jejich závislost na změnách velikosti extracelulárního prostoru.
Links
| MSM0021622404, plan (intention) |
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