| HAVELKOVÁ, Marcela, Zdeňka SVOBODOVÁ, J. KOLÁŘOVÁ, J. KRIJT, Danka NÉMETHOVÁ, Jiří JARKOVSKÝ and R. POSPÍŠIL. Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers. Acta Veterinaria Brno. Brno: University of Veter and Pharm Sciences, 2008, vol. 77, No 1, p. 133-141. ISSN 0001-7213. |
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@article{765188,
author = {Havelková, Marcela and Svobodová, Zdeňka and Kolářová, J. and Krijt, J. and Némethová, Danka and Jarkovský, Jiří and Pospíšil, R.},
article_location = {Brno},
article_number = {1},
keywords = {Cytochrome P450; EROD; vitellogenin; Salmo trutta fario; PCB; river contamination},
language = {eng},
issn = {0001-7213},
journal = {Acta Veterinaria Brno},
title = {Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers},
volume = {77},
year = {2008}
}
TY - JOUR
ID - 765188
AU - Havelková, Marcela - Svobodová, Zdeňka - Kolářová, J. - Krijt, J. - Némethová, Danka - Jarkovský, Jiří - Pospíšil, R.
PY - 2008
TI - Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers
JF - Acta Veterinaria Brno
VL - 77
IS - 1
SP - 133-141
EP - 133-141
PB - University of Veter and Pharm Sciences
SN - 00017213
KW - Cytochrome P450
KW - EROD
KW - vitellogenin
KW - Salmo trutta fario
KW - PCB
KW - river contamination
N2 - This study used biochemical markers to assess contamination at two contaminated sites (Kraliky and Lichkov) and one control site (Cervena Voda) on the River Ticha Orlice, a left-side tributary of the River Elbe. The brown trout was selected as an indicato species. Enzymes of the first stage of xenobiotic conversion, namely cytochrome P450 (CYP 450) and ethoxyresorufin-O-deethylase (EROD) in the liver were selected as biochemical markers. Blood plasma vitellogenin concentrations were used to evaluate xenoestrogenic effects of contamination. Results were compared with the most important inductors of these markers, i.e. with organic pollutants. the highest contamination wit organic pollutants was at Kraliky, and this was reflected in increased cytochrome P450, EROD activity and vitellogenin concentrations. Significant differences were demonstrated in EROD activity and vitellogenin concentrations between Kraliky and Cervena Voda. At the most contaminated site (Kraliky), a significant negative correlation between EROD activity and vitellogenin concentration was demonstrated. This relationship was discussed from the point of view of a possible induction or inhibition of the assessed biomarkers at persistently highly contaminated sites.
ER -
HAVELKOVÁ, Marcela, Zdeňka SVOBODOVÁ, J. KOLÁŘOVÁ, J. KRIJT, Danka NÉMETHOVÁ, Jiří JARKOVSKÝ and R. POSPÍŠIL. Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers. \textit{Acta Veterinaria Brno}. Brno: University of Veter and Pharm Sciences, 2008, vol.~77, No~1, p.~133-141. ISSN~0001-7213.
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