J 2008

Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers

HAVELKOVÁ, Marcela, Zdeňka SVOBODOVÁ, J. KOLÁŘOVÁ, J. KRIJT, Danka NÉMETHOVÁ et. al.

Základní údaje

Originální název

Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers

Název česky

Organic Pollutant Contamination of the River Tichá Orlice as Assessed by Biochemical Markers

Autoři

HAVELKOVÁ, Marcela (203 Česká republika), Zdeňka SVOBODOVÁ (203 Česká republika), J. KOLÁŘOVÁ (203 Česká republika), J. KRIJT (203 Česká republika), Danka NÉMETHOVÁ (703 Slovensko, garant), Jiří JARKOVSKÝ (203 Česká republika) a R. POSPÍŠIL (203 Česká republika)

Vydání

Acta Veterinaria Brno, Brno, University of Veter and Pharm Sciences, 2008, 0001-7213

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.395

Kód RIV

RIV/00216224:14310/08:00025913

Organizační jednotka

Přírodovědecká fakulta

UT WoS

000255001500020

Klíčová slova anglicky

Cytochrome P450; EROD; vitellogenin; Salmo trutta fario; PCB; river contamination

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 28. 6. 2009 21:58, RNDr. Danka Haruštiaková, Ph.D.

Anotace

V originále

This study used biochemical markers to assess contamination at two contaminated sites (Kraliky and Lichkov) and one control site (Cervena Voda) on the River Ticha Orlice, a left-side tributary of the River Elbe. The brown trout was selected as an indicato species. Enzymes of the first stage of xenobiotic conversion, namely cytochrome P450 (CYP 450) and ethoxyresorufin-O-deethylase (EROD) in the liver were selected as biochemical markers. Blood plasma vitellogenin concentrations were used to evaluate xenoestrogenic effects of contamination. Results were compared with the most important inductors of these markers, i.e. with organic pollutants. the highest contamination wit organic pollutants was at Kraliky, and this was reflected in increased cytochrome P450, EROD activity and vitellogenin concentrations. Significant differences were demonstrated in EROD activity and vitellogenin concentrations between Kraliky and Cervena Voda. At the most contaminated site (Kraliky), a significant negative correlation between EROD activity and vitellogenin concentration was demonstrated. This relationship was discussed from the point of view of a possible induction or inhibition of the assessed biomarkers at persistently highly contaminated sites.

Česky

This study used biochemical markers to assess contamination at two contaminated sites (Kraliky and Lichkov) and one control site (Cervena Voda) on the River Ticha Orlice, a left-side tributary of the River Elbe. The brown trout was selected as an indicato species. Enzymes of the first stage of xenobiotic conversion, namely cytochrome P450 (CYP 450) and ethoxyresorufin-O-deethylase (EROD) in the liver were selected as biochemical markers. Blood plasma vitellogenin concentrations were used to evaluate xenoestrogenic effects of contamination. Results were compared with the most important inductors of these markers, i.e. with organic pollutants. the highest contamination wit organic pollutants was at Kraliky, and this was reflected in increased cytochrome P450, EROD activity and vitellogenin concentrations. Significant differences were demonstrated in EROD activity and vitellogenin concentrations between Kraliky and Cervena Voda. At the most contaminated site (Kraliky), a significant negative correlation between EROD activity and vitellogenin concentration was demonstrated. This relationship was discussed from the point of view of a possible induction or inhibition of the assessed biomarkers at persistently highly contaminated sites.

Návaznosti

MSM0021622412, záměr
Název: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Akronym: INCHEMBIOL)
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální , regionální a lokální úrovni