| VOKURKA, Jan, Lucie KLAPUŠOVÁ, Pavla PANTUCKOVA, Martina KUKLETOVÁ, Lubomír KUKLA and Lydie IZAKOVIČOVÁ HOLLÁ. The association of MMP-9 and IL-18 gene promoter polymorphisms with gingivitis in adolescent. Arch Oral Biol. Amsterodam: Elsevier, 2009, vol. 54, No 2, p. 172-178. ISSN 0003-9969. |
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@article{776742,
author = {Vokurka, Jan and Klapušová, Lucie and Pantuckova, Pavla and Kukletová, Martina and Kukla, Lubomír and Izakovičová Hollá, Lydie},
article_location = {Amsterodam},
article_number = {2},
keywords = {gingivitis; gene; polymorphism; IL-18; MMP; interleukin},
language = {eng},
issn = {0003-9969},
journal = {Arch Oral Biol},
title = {The association of MMP-9 and IL-18 gene promoter polymorphisms with gingivitis in adolescent},
volume = {54},
year = {2009}
}
TY - JOUR
ID - 776742
AU - Vokurka, Jan - Klapušová, Lucie - Pantuckova, Pavla - Kukletová, Martina - Kukla, Lubomír - Izakovičová Hollá, Lydie
PY - 2009
TI - The association of MMP-9 and IL-18 gene promoter polymorphisms with gingivitis in adolescent
JF - Arch Oral Biol
VL - 54
IS - 2
SP - 172-178
EP - 172-178
PB - Elsevier
SN - 00039969
KW - gingivitis
KW - gene
KW - polymorphism
KW - IL-18
KW - MMP
KW - interleukin
N2 - Interleukin 18 (IL-18) is shown to be a proinflammatory cytokine that regulates the expression of matrix metalloproteinase 9 (MMP-9). The aim of this study was to test for differences between Czech adolescents with and without gingivitis in relation to MMP-9 and IL-18 polymorphisms. The -1562 T allele of MMP-9 gene could have a role in gingivitis in adolescents. In addition, interaction of the MMP-9 and IL-18 genes could be considered a risk factor for the development of gingivitis in children.
ER -
VOKURKA, Jan, Lucie KLAPUŠOVÁ, Pavla PANTUCKOVA, Martina KUKLETOVÁ, Lubomír KUKLA and Lydie IZAKOVIČOVÁ HOLLÁ. The association of MMP-9 and IL-18 gene promoter polymorphisms with gingivitis in adolescent. \textit{Arch Oral Biol}. Amsterodam: Elsevier, 2009, vol.~54, No~2, p.~172-178. ISSN~0003-9969.
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