| BROŽKOVÁ, Kristýna, Eva BUDINSKÁ, Pavel BOUCHAL, Lenka HERNYCHOVÁ, Dana KNOFLÍČKOVÁ, Dalibor VALÍK, Rostislav VYZULA, Bořivoj VOJTĚŠEK a Rudolf NENUTIL. Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression. Breast Cancer Research. London, Great Britain: Biomed Central Ltd., 2008, roč. 10, č. 3, s. R48, 11 s. ISSN 1465-5411. Dostupné z: https://dx.doi.org/10.1186/bcr2101. |
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@article{792456,
author = {Brožková, Kristýna and Budinská, Eva and Bouchal, Pavel and Hernychová, Lenka and Knoflíčková, Dana and Valík, Dalibor and Vyzula, Rostislav and Vojtěšek, Bořivoj and Nenutil, Rudolf},
article_location = {London, Great Britain},
article_number = {3},
doi = {http://dx.doi.org/10.1186/bcr2101},
keywords = {breast cancer; SELDI-TOF MS; cDNA clusters},
language = {eng},
issn = {1465-5411},
journal = {Breast Cancer Research},
title = {Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression},
volume = {10},
year = {2008}
}
TY - JOUR
ID - 792456
AU - Brožková, Kristýna - Budinská, Eva - Bouchal, Pavel - Hernychová, Lenka - Knoflíčková, Dana - Valík, Dalibor - Vyzula, Rostislav - Vojtěšek, Bořivoj - Nenutil, Rudolf
PY - 2008
TI - Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression
JF - Breast Cancer Research
VL - 10
IS - 3
SP - R48
EP - R48
PB - Biomed Central Ltd.
SN - 14655411
KW - breast cancer
KW - SELDI-TOF MS
KW - cDNA clusters
N2 - Microarray-based gene expression profiling represents a major breakthrough for understanding the molecular complexity of breast cancer. cDNA expression profiles cannot detect changes in activities that arise from posttranslational modifications, however, and therefore do not provide a complete picture of all biologically important changes that occur in tumors. Additional opportunities to identify and/or validate molecular signatures of breast carcinomas are provided by proteomic approaches. Surface-enhanced laser desorption/ ionization time-of-flight mass spectrometry (SELDI-TOF MS) offers high-throughput protein profiling, leading to extraction of protein array data, calling for effective and appropriate use of bioinformatics and statistical tools.
ER -
BROŽKOVÁ, Kristýna, Eva BUDINSKÁ, Pavel BOUCHAL, Lenka HERNYCHOVÁ, Dana KNOFLÍČKOVÁ, Dalibor VALÍK, Rostislav VYZULA, Bořivoj VOJTĚŠEK a Rudolf NENUTIL. Surface-enhanced laser desorption/ionization time-of-flight proteomic profiling of breast carcinomas identifies clinicopathologically relevant groups of patients similar to previously defined clusters from cDNA expression. \textit{Breast Cancer Research}. London, Great Britain: Biomed Central Ltd., 2008, roč.~10, č.~3, s.~R48, 11 s. ISSN~1465-5411. Dostupné z: https://dx.doi.org/10.1186/bcr2101.
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