The profile and prognosis of patients hospitalised with heart
failure. The value of discharge blood pressure and cholesterol

J 2008

The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure and cholesterol

ŠPINAR, Jindřich; Ondřej LUDKA; Viktor MUSIL; Zbyněk POZDÍŠEK; T. PAVLÍK et al.

Základní údaje

Originální název

The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure and cholesterol

Název česky

Profil a prognóza nemocného hospitalizovaného se srdečním selháním. Význam krevního tlaku a cholesterolu.

Autoři

ŠPINAR, Jindřich; Ondřej LUDKA; Viktor MUSIL; Zbyněk POZDÍŠEK; T. PAVLÍK; Ladislav DUŠEK; Jiří VÍTOVEC; Lenka ŠPINAROVÁ a Miroslav SOUČEK

Vydání

International Heart Journal, 2008, 1349-2365

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 0.947

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/08:00027663

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

profile prognosis heart failure cholesterol

Změněno: 31. 3. 2010 12:48, RNDr. Tomáš Pavlík, Ph.D.

Anotace

ORIG CZ

V originále

The aim of the present prospective, single centre observational study was to describe the profile and prognosis of patients hospitalised with chronic heart failure and to determine the value of discharge blood pressure and cholesterol for long-term survival. From among 2,346 hospitalised patients, 320 (13.6%) suffered from chronic heart failure and 28 (8.8%) died during hospitalisation. The in-patient mortality rate was similar to that in patients not suffering from chronic heart failure (P = 0, 3). Of 292 patients who were discharged, 162 (55%) died during the subsequent 5 years. The predetermined parameters of pure prognosis were associated with lower diastolic blood pressure (P = 0.008) and lower cholesterol (P = 0.012). A poor prognosis was associated with lower systolic blood pressure plus lower cholesterol and lower diastolic blood pressure and lower cholesterol. Other independent prognostic parameters were older age (P less than 0.001), higher heart rate (P = 0.02), higher creatinine (P less than 0.001), higher urea (P less than 0.001), higher uric acid (P < 0.001), lower hemoglobin (P = 0.02), lower ejection fraction (P = 0.080), and a history of ischemic heart disease (P less than 0.01). Patients suffering from chronic heart failure and discharged home have a worse prognosis if their systolic and/or diastolic blood pressures and/or cholesterol levels are too low. The optimal values seem to be levels that are around the recommended targets, that is a systolic BP of 140 mmHg, diastolic BP of 90 mmHg, and a cholesterol level of 5 mmol/L.

Česky

Tento článek se zabývá vlivem krevního tlaku a hladiny cholesterolu při propuštění pacienta, hospitalizovaného pro srdeční selhání, na celkové přežití pacienta kalkulovaného od okamžiku propuštění.

Návaznosti

MSM0021622402, záměr

Název: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob

Citovat

ŠPINAR, Jindřich; Ondřej LUDKA; Viktor MUSIL; Zbyněk POZDÍŠEK; T. PAVLÍK; Ladislav DUŠEK; Jiří VÍTOVEC; Lenka ŠPINAROVÁ a Miroslav SOUČEK. The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure and cholesterol. International Heart Journal. 2008, roč. 49, č. 6, 15 s. ISSN 1349-2365.

@article{817590,
   author = {Špinar, Jindřich and Ludka, Ondřej and Musil, Viktor and Pozdíšek, Zbyněk and Pavlík, T. and Dušek, Ladislav and Vítovec, Jiří and Špinarová, Lenka and Souček, Miroslav},
   article_number = {6},
   keywords = {profile prognosis heart failure cholesterol},
   language = {eng},
   issn = {1349-2365},
   journal = {International Heart Journal},
   title = {The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure and cholesterol},
   volume = {49},
   year = {2008}
}

TY  - JOUR
ID  - 817590
AU  - Špinar, Jindřich - Ludka, Ondřej - Musil, Viktor - Pozdíšek, Zbyněk - Pavlík, T. - Dušek, Ladislav - Vítovec, Jiří - Špinarová, Lenka - Souček, Miroslav
PY  - 2008
TI  - The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure and cholesterol
JF  - International Heart Journal
VL  - 49
IS  - 6
SN  - 13492365
KW  - profile prognosis heart failure cholesterol
N2  - The aim of the present prospective, single centre observational study was to describe the profile and prognosis of patients hospitalised with chronic heart failure and to determine the value of discharge blood pressure and cholesterol for long-term survival. From among 2,346 hospitalised patients, 320 (13.6%) suffered from chronic heart failure and 28 (8.8%) died during hospitalisation. The in-patient mortality rate was similar to that in patients not suffering from chronic heart failure (P = 0, 3). Of 292 patients who were discharged, 162 (55%) died during the subsequent 5 years. The predetermined parameters of pure prognosis were associated with lower diastolic blood pressure (P = 0.008) and lower cholesterol (P = 0.012). A poor prognosis was associated with lower systolic blood pressure plus lower cholesterol and lower diastolic blood pressure and lower cholesterol. Other independent prognostic parameters were older age (P less than 0.001), higher heart rate (P = 0.02), higher creatinine (P less than 0.001), higher urea (P less than 0.001), higher uric acid (P < 0.001), lower hemoglobin (P = 0.02), lower ejection fraction (P = 0.080), and a history of ischemic heart disease (P less than 0.01). Patients suffering from chronic heart failure and discharged home have a worse prognosis if their systolic and/or diastolic blood pressures and/or cholesterol levels are too low. The optimal values seem to be levels that are around the recommended targets, that is a systolic BP of 140 mmHg, diastolic BP of 90 mmHg, and a cholesterol level of 5 mmol/L.
ER  -

ŠPINAR, Jindřich; Ondřej LUDKA; Viktor MUSIL; Zbyněk POZDÍŠEK; T. PAVLÍK; Ladislav DUŠEK; Jiří VÍTOVEC; Lenka ŠPINAROVÁ a Miroslav SOUČEK. The profile and prognosis of patients hospitalised with heart failure. The value of discharge blood pressure and cholesterol. \textit{International Heart Journal}. 2008, roč.~49, č.~6, 15 s. ISSN~1349-2365.

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