Vagus nerve stimulation: Longitudinal follow-up patients
treated for 5 years.

J 2009

Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.

KUBA, Robert; Milan BRÁZDIL; Miroslav KALINA; Tomáš PROCHÁZKA; Jiří HOVORKA et. al.

Základní údaje

Originální název

Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.

Název česky

Stimulace nervus vagus: Dlouhodobé sledování pacientů léčených 5 let.

Autoři

Vydání

Seizure, 2009, 1059-1311

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.233

Kód RIV

RIV/00216224:14110/09:00051164

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.seizure.2008.10.012

UT WoS

000265465000007

Klíčová slova anglicky

vagus nerve stimulation; efficacy; long-term outcome; comlications

Štítky

comlications, efficacy, long-term outcome, vagus nerve stimulation

Příznaky

Mezinárodní význam

Změněno: 20. 4. 2012 10:59, Mgr. Michal Petr

Anotace

ORIG CZ

V originále

We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up 64.4% of patients were responders, 15.5% experienced >= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole group. Complications and chronic adverse effects occurred in 13.3% of patients. VNS is an effective and safe method to refractory epilepsy in common clinical practice.

Česky

Stimulace nervus vagus: Dlouhodobé sledování pacientů léčených 5 let.

Citovat

KUBA, Robert; Milan BRÁZDIL; Miroslav KALINA; Tomáš PROCHÁZKA; Jiří HOVORKA; Tomáš NEŽÁDAL; Jan HADAČ; Klára BROŽOVÁ; Věra SEBROŇOVÁ; Vladimír KOMÁREK; Petr MARUSIČ; Hana OŠLEJŠKOVÁ; Jana ZARUBOVA a Ivan REKTOR. Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years. Seizure. 2009, roč. 18, č. 4, s. 269-274. ISSN 1059-1311. Dostupné z: https://doi.org/10.1016/j.seizure.2008.10.012.

@article{837053,
   author = {Kuba, Robert and Brázdil, Milan and Kalina, Miroslav and Procházka, Tomáš and Hovorka, Jiří and Nežádal, Tomáš and Hadač, Jan and Brožová, Klára and Sebroňová, Věra and Komárek, Vladimír and Marusič, Petr and Ošlejšková, Hana and Zarubova, Jana and Rektor, Ivan},
   article_number = {4},
   doi = {https://doi.org/10.1016/j.seizure.2008.10.012},
   keywords = {vagus nerve stimulation; efficacy; long-term outcome; comlications},
   language = {eng},
   issn = {1059-1311},
   journal = {Seizure},
   title = {Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.},
   volume = {18},
   year = {2009}
}

TY  - JOUR
ID  - 837053
AU  - Kuba, Robert - Brázdil, Milan - Kalina, Miroslav - Procházka, Tomáš - Hovorka, Jiří - Nežádal, Tomáš - Hadač, Jan - Brožová, Klára - Sebroňová, Věra - Komárek, Vladimír - Marusič, Petr - Ošlejšková, Hana - Zarubova, Jana - Rektor, Ivan
PY  - 2009
TI  - Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.
JF  - Seizure
VL  - 18
IS  - 4
SP  - 269-274
EP  - 269-274
SN  - 10591311
KW  - vagus nerve stimulation
KW  - efficacy
KW  - long-term outcome
KW  - comlications
N2  - We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up 64.4% of patients were responders, 15.5% experienced >= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole group. Complications and chronic adverse effects occurred in 13.3% of patients. VNS is an effective and safe method to refractory epilepsy in common clinical practice.
ER  -

KUBA, Robert; Milan BRÁZDIL; Miroslav KALINA; Tomáš PROCHÁZKA; Jiří HOVORKA; Tomáš NEŽÁDAL; Jan HADAČ; Klára BROŽOVÁ; Věra SEBROŇOVÁ; Vladimír KOMÁREK; Petr MARUSIČ; Hana OŠLEJŠKOVÁ; Jana ZARUBOVA a Ivan REKTOR. Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years. \textit{Seizure}. 2009, roč.~18, č.~4, s.~269-274. ISSN~1059-1311. Dostupné z: https://doi.org/10.1016/j.seizure.2008.10.012.

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