Second autologous transplantation for multiple myeloma patients
relapsing after the first autograft -- a pilot study for the
evaluation of experimental maintenance therapies. Report of the
prospective non-randomized pilot study of the Czech Myeloma
Group

J 2004

Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group

KŘIVANOVÁ, Andrea; Roman HÁJEK; Marta KREJČÍ; Vlastimil ŠČUDLA; Karel INDRÁK et al.

Základní údaje

Originální název

Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group

Název česky

Druhá autologní transplantace u pacientů s MM relabovaných po prvním autoštěpu - pilotní studie pro zhodnocení experimentální udržovací léčby

Autoři

KŘIVANOVÁ, Andrea; Roman HÁJEK; Marta KREJČÍ; Vlastimil ŠČUDLA; Karel INDRÁK; J. BAČOVSKÝ; Tomáš BÜCHLER; A. SVOBODNÍK; Zdeněk ADAM; Jiří MAYER a Jiří VORLÍČEK

Vydání

Onkologie, Switzerland, Karger, 2004, 0378-584X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.283

Označené pro přenos do RIV

Ano

Organizační jednotka

Lékařská fakulta

UT WoS

000222477400007

Klíčová slova česky

mnohočetný myelom; autologní transplantace

Klíčová slova anglicky

multiple myeloma; autologous transplantation

Štítky

autologous transplantation, multiple myeloma

Změněno: 23. 6. 2009 13:53, Mgr. Anna Potáčová, Ph.D.

Anotace

ORIG CZ

V originále

High-dose chemotherapy followed by autologous stem cell transplantation (AT) is accepted as first-line therapy for patients with multiple myeloma (MM), with very good tolerance and low mortality (2-3%). We tested repeated transplantation with different experimental maintenance therapies in patients with MM relapsing/progressing after first AT. Results were compared using intra-individual analyses, therefore inter-individual differences are excluded (T2 model). Repeated AT is a feasible and successful strategy in treatment of relapsing MM; response to second AT and toxicity were acceptable and similar to the first AT in our assessment.

Česky

V článku je popsán výsledek studie, při níž byla testována druhá autologní transplantace u pacientů s MM.

Citovat

KŘIVANOVÁ, Andrea; Roman HÁJEK; Marta KREJČÍ; Vlastimil ŠČUDLA; Karel INDRÁK; J. BAČOVSKÝ; Tomáš BÜCHLER; A. SVOBODNÍK; Zdeněk ADAM; Jiří MAYER a Jiří VORLÍČEK. Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group. Onkologie. Switzerland: Karger, 2004, roč. 27, č. 3, s. 275-279. ISSN 0378-584X.

@article{837994,
   author = {Křivanová, Andrea and Hájek, Roman and Krejčí, Marta and Ščudla, Vlastimil and Indrák, Karel and Bačovský, J. and Büchler, Tomáš and Svobodník, A. and Adam, Zdeněk and Mayer, Jiří and Vorlíček, Jiří},
   article_location = {Switzerland},
   article_number = {3},
   keywords = {multiple myeloma; autologous transplantation},
   language = {eng},
   issn = {0378-584X},
   journal = {Onkologie},
   title = {Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group},
   volume = {27},
   year = {2004}
}

TY  - JOUR
ID  - 837994
AU  - Křivanová, Andrea - Hájek, Roman - Krejčí, Marta - Ščudla, Vlastimil - Indrák, Karel - Bačovský, J. - Büchler, Tomáš - Svobodník, A. - Adam, Zdeněk - Mayer, Jiří - Vorlíček, Jiří
PY  - 2004
TI  - Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group
JF  - Onkologie
VL  - 27
IS  - 3
SP  - 275-279
EP  - 275-279
PB  - Karger
SN  - 0378584X
KW  - multiple myeloma
KW  - autologous transplantation
N2  - High-dose chemotherapy followed by autologous stem cell transplantation (AT) is accepted as first-line therapy for patients with multiple myeloma (MM), with very good tolerance and low mortality (2-3%). We tested repeated transplantation with different experimental maintenance therapies in patients with MM relapsing/progressing after first AT. Results were compared using intra-individual analyses, therefore inter-individual differences are excluded (T2 model). Repeated AT is a feasible and successful strategy in treatment of relapsing MM; response to second AT and toxicity were acceptable and similar to the first AT in our assessment.
ER  -

KŘIVANOVÁ, Andrea; Roman HÁJEK; Marta KREJČÍ; Vlastimil ŠČUDLA; Karel INDRÁK; J. BAČOVSKÝ; Tomáš BÜCHLER; A. SVOBODNÍK; Zdeněk ADAM; Jiří MAYER a Jiří VORLÍČEK. Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech Myeloma Group. \textit{Onkologie}. Switzerland: Karger, 2004, roč.~27, č.~3, s.~275-279. ISSN~0378-584X.

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