2009
Metazoan parasites and balancing selection at MHC class IIB genes in the wild populations of freshwater cyprinid fish (Leuciscus cephalus)
SEIFERTOVÁ, Mária a Andrea VETEŠNÍKOVÁ ŠIMKOVÁZákladní údaje
Originální název
Metazoan parasites and balancing selection at MHC class IIB genes in the wild populations of freshwater cyprinid fish (Leuciscus cephalus)
Název česky
Mnohobuneční paraziti a balanční selekce MHC genů v divokých populacích jelce tlouště (Leuciscus cephalus)
Vydání
17th Helminthological days 2009, 2009
Další údaje
Jazyk
angličtina
Typ výsledku
Konferenční abstrakt
Obor
10600 1.6 Biological sciences
Stát vydavatele
Česká republika
Utajení
není předmětem státního či obchodního tajemství
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14310/09:00042632
Organizační jednotka
Přírodovědecká fakulta
ISBN
978-80-210-4887-4
Klíčová slova česky
balanční selekce MHC jelec tlouť
Klíčová slova anglicky
balancing selection MHC chub
Příznaky
Mezinárodní význam
Změněno: 8. 3. 2011 09:52, Mgr. Mária Seifertová, Ph.D.
V originále
Major histocompatibility complex (MHC) genes are highly polymorphic. The high level of nucleotide and allelic diversity is maintained by balancing or parasite driven selection. In this study, we investigated the metazoan parasite load and MHC diversity in fifteen chub (Leuciscus cephalus) populations in Europe. The exon 2 of DAB genes (MHC class IIB) was selected for sequence analysis considering that this part of DAB genes encodes the major parts of the PBR (peptide binding regions) as the most polymorphic parts in many class II genes. Likewise, twelve microsatellite loci were studied to elucidate the role of neutral evolutionary processes on MHC variability. Spearman correlation analysis revealed an influence of geographic distance and genetic distance on similarity between metazoan parasite communities. Within individual fish the highest mean variability in parasite abundance and mean species parasite richness were associated with the maximal number of alleles.
Česky
Major histocompatibility complex (MHC) genes are highly polymorphic. The high level of nucleotide and allelic diversity is maintained by balancing or parasite driven selection. In this study, we investigated the metazoan parasite load and MHC diversity in fifteen chub (Leuciscus cephalus) populations in Europe. The exon 2 of DAB genes (MHC class IIB) was selected for sequence analysis considering that this part of DAB genes encodes the major parts of the PBR (peptide binding regions) as the most polymorphic parts in many class II genes. Likewise, twelve microsatellite loci were studied to elucidate the role of neutral evolutionary processes on MHC variability. Spearman correlation analysis revealed an influence of geographic distance and genetic distance on similarity between metazoan parasite communities. Within individual fish the highest mean variability in parasite abundance and mean species parasite richness were associated with the maximal number of alleles.
Návaznosti
| GA524/07/0188, projekt VaV |
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| LC522, projekt VaV |
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| MSM0021622416, záměr |
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