LIPOVÝ, Břetislav, Yvona KALOUDOVÁ, Miloslava MATÝŠKOVÁ, Miroslav PENKA, Hana ŘIHOVÁ a Pavel BRYCHTA. HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC. Acta chirurgiae plasticae. Praha, 2008, roč. 50, č. 4, s. 115-118, 120 s. ISSN 1803-6597.
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Základní údaje
Originální název HEMOCOAGULATION DISORDERS IN EXTENSIVELY BURNED PATIENTS: PILOT STUDY FOR SCORING OF THE DIC
Název česky Hemokoagulační poruchy u těžce popálených pacientů: pilotní studie ke skórování DIC
Autoři LIPOVÝ, Břetislav (203 Česká republika, garant), Yvona KALOUDOVÁ (203 Česká republika), Miloslava MATÝŠKOVÁ (203 Česká republika), Miroslav PENKA (203 Česká republika), Hana ŘIHOVÁ (203 Česká republika) a Pavel BRYCHTA (203 Česká republika).
Vydání Acta chirurgiae plasticae, Praha, 2008, 1803-6597.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30200 3.2 Clinical medicine
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Kód RIV RIV/00216224:14110/08:00036699
Organizační jednotka Lékařská fakulta
Klíčová slova anglicky DIC haemocoagulation assesment burn trauma D dimers
Příznaky Recenzováno
Změnil Změnil: prof. MUDr. Břetislav Lipový, Ph.D., MBA, LL.M., učo 60248. Změněno: 4. 2. 2010 20:50.
Anotace
Goal of the study. To apply results of the hemocoagulation parameters to the DIC (disseminated intravascular coagulation) score system. Compare parameters of the DIC score in patients with extensive burn trauma (hospitalized at the Intensive Care Unit, ICU) and patients with lesser extent of burn injury (hospitalized at the standard unit). To use these data within the evidence based medicine for the prediction of organ damage and multi organ failure. Type of study. Prospective study. Material and methods. We have included total of 36 patients in the group within four months. Twelve patients were hospitalized at the ICU, 24 patients were hospitalized at the intermedial care and standard unit. Repeatedly, we have taken blood from patients to evaluate the hemocoagulation parameters. In patients hospitalized at the ICU, the blood was taken from the central vein (prior to the drawn, the access was flushed with 100ml of F1/1, the blood was taken from different access than from the one administering heparin), in patients hospitalized at the standard unit the blood was taken from a peripheral vein. The results were then put into the tables established according to the ISTH (International Society on Thrombosis and Hemostasis). Next, the DIC score was calculated to predict severity of hemocoagulation balance disorders in burn trauma, or occurrence of complications during the treatment. Results. Part 1: We have evaluated 12 patients (4 females) hospitalized at the ICU. At the day of injury the overt DIC score reached 1.25 (0 3), fifth day after the injury the average value of overt DIC score was 1.83 (0 3), one day after the autotransplantation it was 2.08 (0 3) and at the day of discharge from the hospital 0. In the deceased patient the DIC score reached value of 2. Part 2: We evaluated 24 patients (10 females) hospitalized at the standard unit. The extent of their burn injury was 5.9% TBSA (0.5 12% TBSA), age 49.13 years (17 94 years). At the day of injury the overt DIC score reached 0.25 (0 2). Fifth day after the injury the average value of overt DIC score was 1.66 (0 2). Day after the autotransplantation it was 1.83 (0 3) and at the day of discharge 0.02 (0 2). Conclusion. During the treatment of the patients with various extent of burn injury, none of the patients scores reached values that would mean occurrence of obvious overt DIC.
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