2009
Critical illness polyneuromyopathy - a well-known but still controversial entity
BEDNAŘÍK, Josef a Petr VONDRÁČEKZákladní údaje
Originální název
Critical illness polyneuromyopathy - a well-known but still controversial entity
Název česky
Polyneuromyopatie kritického stavu - dobře známá, ale stále kontroverzní entita
Autoři
Vydání
Scripta Medica, Brno, Masarykova univerzita, 2009, 1211-3395
Další údaje
Typ výsledku
Článek v odborném periodiku
Utajení
není předmětem státního či obchodního tajemství
Označené pro přenos do RIV
Ne
Organizační jednotka
Lékařská fakulta
Klíčová slova anglicky
critical illness; polyneuropathy; myopathy
Příznaky
Recenzováno
Změněno: 18. 1. 2010 11:39, Ing. Dagmar Kratochvílová
Anotace
V originále
Two main clinical, pathological and electrophysiological types of acquired neuromuscular involvement in critically ill patients have been described in the past two decades: critical illness polyneuropathy and critical illness myopathy. However, there, still exist many controversies and unresolved questions regarding definition, terminology, diagnosis, and differentiation of what appears to be a spectrum of more or less overlapping neuromuscular disorders rather than distinct entities, and recently a new term - critical illness polyneuromyopathy (CIPM) has been coined. CIPM may present with muscle weakness and failure to wean from mechanical ventilation, but is discovered more often and earlier by electrophysiological examination. In this review, the incidence, clinical, electrophysiological and histopathological features, and risk factors of CIPM will be described. Among the most important risk factors for CIPM are sepsis or systemic inflammatory response syndrome and the severity of multi-organ failure. Acquired neuromuscular weakness in critically ill patients should be regarded as a part rather than a complication of critical illness - dysfunction or failure of a further (neuromuscular) system.