J 2009

Critical illness polyneuromyopathy - a well-known but still controversial entity

BEDNAŘÍK, Josef a Petr VONDRÁČEK

Základní údaje

Originální název

Critical illness polyneuromyopathy - a well-known but still controversial entity

Název česky

Polyneuromyopatie kritického stavu - dobře známá, ale stále kontroverzní entita

Vydání

Scripta Medica, Brno, Masarykova univerzita, 2009, 1211-3395

Další údaje

Typ výsledku

Článek v odborném periodiku

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ne

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

critical illness; polyneuropathy; myopathy

Příznaky

Recenzováno
Změněno: 18. 1. 2010 11:39, Ing. Dagmar Kratochvílová

Anotace

V originále

Two main clinical, pathological and electrophysiological types of acquired neuromuscular involvement in critically ill patients have been described in the past two decades: critical illness polyneuropathy and critical illness myopathy. However, there, still exist many controversies and unresolved questions regarding definition, terminology, diagnosis, and differentiation of what appears to be a spectrum of more or less overlapping neuromuscular disorders rather than distinct entities, and recently a new term - critical illness polyneuromyopathy (CIPM) has been coined. CIPM may present with muscle weakness and failure to wean from mechanical ventilation, but is discovered more often and earlier by electrophysiological examination. In this review, the incidence, clinical, electrophysiological and histopathological features, and risk factors of CIPM will be described. Among the most important risk factors for CIPM are sepsis or systemic inflammatory response syndrome and the severity of multi-organ failure. Acquired neuromuscular weakness in critically ill patients should be regarded as a part rather than a complication of critical illness - dysfunction or failure of a further (neuromuscular) system.