a 2009

TRAMP-mediated spliceosomal intron turnover

LALÁKOVÁ, Jana a Štěpánka VAŇÁČOVÁ

Základní údaje

Originální název

TRAMP-mediated spliceosomal intron turnover

Název česky

TRAMP-mediated spliceosomal intron turnover

Autoři

LALÁKOVÁ, Jana a Štěpánka VAŇÁČOVÁ

Vydání

RNA Club 2009, 2009

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

Genetika a molekulární biologie

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Označené pro přenos do RIV

Ne

Organizační jednotka

Přírodovědecká fakulta

ISSN

Klíčová slova česky

RNA Club

Klíčová slova anglicky

RNA Club

Příznaky

Mezinárodní význam
Změněno: 9. 4. 2010 10:59, prof. Mgr. Štěpánka Vaňáčová, Ph.D.

Anotace

ORIG CZ

V originále

In higher eukaryotes, most protein-encoding genes contain intronic sequences that need to be removed from the precursor messenger RNAs (pre-mRNAs). The intron splicing occurs in two main catalytic steps, in which introns are removed from primary transcripts in lariat forms. This process is performed by the spliceosome that is composed of five small nuclear ribonucleoprotein particles (snRNPs) and non-snRNP protein factors that bind to the pre-mRNA. The mechanism of intron removal has been described to a great detail, however, little is known about the intron degradation

Česky

In higher eukaryotes, most protein-encoding genes contain intronic sequences that need to be removed from the precursor messenger RNAs (pre-mRNAs). The intron splicing occurs in two main catalytic steps, in which introns are removed from primary transcripts in lariat forms. This process is performed by the spliceosome that is composed of five small nuclear ribonucleoprotein particles (snRNPs) and non-snRNP protein factors that bind to the pre-mRNA. The mechanism of intron removal has been described to a great detail, however, little is known about the intron degradation