Portable capillary-based (non-chip) capillary electrophoresis

J 2010

Portable capillary-based (non-chip) capillary electrophoresis

RYVOLOVÁ, Markéta; Jan PREISLER; Dermot BRABAZON, a Miroslav MACKA

Základní údaje

Originální název

Portable capillary-based (non-chip) capillary electrophoresis

Název česky

Přenosné kapilární (nečipové) elektroforézy

Autoři

RYVOLOVÁ, Markéta; Jan PREISLER; Dermot BRABAZON, a Miroslav MACKA

Vydání

Trends in Analytical Chemistry, 2010, 0165-9936

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10406 Analytical chemistry

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 6.602

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/10:00043699

Organizační jednotka

Přírodovědecká fakulta

UT WoS

000276878500022

Klíčová slova anglicky

Capillary electrophoresis (CE); Chemiluminescence detection (CLD); Electrochemical detection (ECD); Injection; Laser diode (LD); Lightemitting

Změněno: 9. 4. 2013 10:50, prof. Mgr. Jan Preisler, Ph.D.

Anotace

ORIG CZ

V originále

Miniaturized, portable instrumentation has been gaining popularity in all areas of analytical chemistry. Capillary electrophoresis (CE), due to its main strengths of high separation efficiency, relatively short analysis time and low consumption of chemicals, is a particularly suitable technique for use in portable analytical instrumentation. In line with the general trend in miniaturization in chemistry utilizing microfluidic chips, the main thrust of portable CE (P-CE) systems development is towards chip-based miniaturized CE. Despite this, capillary-based (non-chip) P-CE systems have certain unmatched advantages, especially in the relative simplicity of the regular cylindrical geometry of the CE capillary, maximal volume-to-surface ratio, no need to design and to fabricate a chip, the low costs of capillary compared to chip, and better performance with some detection techniques. This review presents an overview of the state of the art of P-CE and literature relevant to future developments. We pay particular attention to the development and the potential of miniaturization of functional parts for P-CE. These include components related to sample introduction, separation and detection, which are the key elements in P-CE design. The future of P-CE may be in relatively simple, rugged designs (e.g., using a short piece of capillary fixed to a chip-sized platform on which injection and detection parts can be mounted). Electrochemical detection is well suited for miniaturization, so is probably the most suitable detection technique for P-CE, but optical detection is gaining interest, especially due to miniaturized light sources (e.g., light emitting diodes).

Česky

Abstrakt titulu Přenosné kapilární (nečipové) elektroforézy viz anglická verze

Návaznosti

GA203/09/1025, projekt VaV

Název: Multidetekční platforma pro mikrokolonové separace proteinů a peptidů

Investor: Grantová agentura ČR, Multidetekční platforma pro mikrokolonové separace proteinů a peptidů

MSM0021622415, záměr

Název: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Molekulární podstata buněčných a tkáňových regulací

Citovat

RYVOLOVÁ, Markéta; Jan PREISLER; Dermot BRABAZON, a Miroslav MACKA. Portable capillary-based (non-chip) capillary electrophoresis. Trends in Analytical Chemistry. 2010, roč. 29, č. 4, s. 339-353, 14 s. ISSN 0165-9936.

@article{879296,
   author = {Ryvolová, Markéta and Preisler, Jan and Brabazon,, Dermot and Macka, Miroslav},
   article_number = {4},
   keywords = {Capillary electrophoresis (CE); Chemiluminescence detection (CLD); Electrochemical detection (ECD); Injection; Laser diode (LD); Lightemitting},
   language = {eng},
   issn = {0165-9936},
   journal = {Trends in Analytical Chemistry},
   title = {Portable capillary-based (non-chip) capillary electrophoresis},
   volume = {29},
   year = {2010}
}

TY  - JOUR
ID  - 879296
AU  - Ryvolová, Markéta - Preisler, Jan - Brabazon,, Dermot - Macka, Miroslav
PY  - 2010
TI  - Portable capillary-based (non-chip) capillary electrophoresis
JF  - Trends in Analytical Chemistry
VL  - 29
IS  - 4
SP  - 339-353
EP  - 339-353
SN  - 01659936
KW  - Capillary electrophoresis (CE)
KW  - Chemiluminescence detection (CLD)
KW  - Electrochemical detection (ECD)
KW  - Injection
KW  - Laser diode (LD)
KW  - Lightemitting
N2  - Miniaturized, portable instrumentation has been gaining popularity in all areas of analytical chemistry. Capillary electrophoresis (CE), due to its main strengths of high separation efficiency, relatively short analysis time and low consumption of chemicals, is a particularly suitable technique for use in portable analytical instrumentation. In line with the general trend in miniaturization in chemistry utilizing microfluidic chips, the main thrust of portable CE (P-CE) systems development is towards chip-based miniaturized CE. Despite this, capillary-based (non-chip) P-CE systems have certain unmatched advantages, especially in the relative simplicity of the regular cylindrical geometry of the CE capillary, maximal volume-to-surface ratio, no need to design and to fabricate a chip, the low costs of capillary compared to chip, and better performance with some detection techniques. This review presents an overview of the state of the art of P-CE and literature relevant to future developments. We pay particular attention to the development and the potential of miniaturization of functional parts for P-CE. These include components related to sample introduction, separation and detection, which are the key elements in P-CE design. The future of P-CE may be in relatively simple, rugged designs (e.g., using a short piece of capillary fixed to a chip-sized platform on which injection and detection parts can be mounted). Electrochemical detection is well suited for miniaturization, so is probably the most suitable detection technique for P-CE, but optical detection is gaining interest, especially due to miniaturized light sources (e.g., light emitting diodes).
ER  -

RYVOLOVÁ, Markéta; Jan PREISLER; Dermot BRABAZON, a Miroslav MACKA. Portable capillary-based (non-chip) capillary electrophoresis. \textit{Trends in Analytical Chemistry}. 2010, roč.~29, č.~4, s.~339-353, 14 s. ISSN~0165-9936.

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