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@proceedings{888214,
author = {Foltánková, Veronika and Koláčná, Kateřina and Matějková, Eva and Smejkalová, Jana and Michálek, Jaroslav},
booktitle = {15th Congress of the European Hematology Association},
keywords = {Angiogenesis; Cellular therapy; Immunomodulation; Mesenchymal cells},
language = {eng},
title = {Manufacturing of bone marrow-derived mesenchymal stromal cells according to GMP requirements for clinical trials},
year = {2010}
}
TY - CONF
ID - 888214
AU - Foltánková, Veronika - Koláčná, Kateřina - Matějková, Eva - Smejkalová, Jana - Michálek, Jaroslav
PY - 2010
TI - Manufacturing of bone marrow-derived mesenchymal stromal cells according to GMP requirements for clinical trials
KW - Angiogenesis
KW - Cellular therapy
KW - Immunomodulation
KW - Mesenchymal cells
N2 - MSCs are resident in the bone marrow in small numbers of nucleated cells (0.001-0.01%), but can be readily expanded in vitro to provide sufficient number of GMP grade cells for local and systemic cellular therapy. The methods used in the manufacturing protocol will be validated and the clinical protocol will be approved by Czech State Institute for Drug Control.
ER -
FOLTÁNKOVÁ, Veronika, Kateřina KOLÁČNÁ, Eva MATĚJKOVÁ, Jana SMEJKALOVÁ a Jaroslav MICHÁLEK. Manufacturing of bone marrow-derived mesenchymal stromal cells according to GMP requirements for clinical trials. In \textit{15th Congress of the European Hematology Association}. 2010. ISSN~0390-6078.
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