| PAVLÍKOVÁ, Nela, Kortner TROND M. a Augustine ARUKWE. Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator. Aquatic toxicology. 2010, roč. 99, č. 2, 10 s. ISSN 0166-445X. |
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@article{891931,
author = {Pavlíková, Nela and Trond M., Kortner and Arukwe, Augustine},
article_number = {2},
keywords = {Tributyltin; Forskolin; Endocrine disruption; Liver; PPAR; Aromatase; CYP3A; Salmon},
language = {eng},
issn = {0166-445X},
journal = {Aquatic toxicology},
title = {Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator},
volume = {99},
year = {2010}
}
TY - JOUR
ID - 891931
AU - Pavlíková, Nela - Trond M., Kortner - Arukwe, Augustine
PY - 2010
TI - Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator
JF - Aquatic toxicology
VL - 99
IS - 2
SN - 0166445X
KW - Tributyltin
KW - Forskolin
KW - Endocrine disruption
KW - Liver
KW - PPAR
KW - Aromatase
KW - CYP3A
KW - Salmon
N2 - The purpose of this study was to explore effect of TBT on expression of genes involved in estrogenic responses, fat and glucose metabolism and metabolic pathways common for xenobiotics and TBT interaction with cAMP signaling towards these genes. Atlantic salmon (salmo salar) was exposed to three concentrations of TBT and consequently to forskolin (an adenylyl cyclase activator). The mRNA expression and protein levels of estrogenic receptor, peroxisome proliferator-activated receptors, ACOX-1, pregnane X receptor, CYP3A and GST in salmon liver were determined using QRT-PCR and western-blotting.
ER -
PAVLÍKOVÁ, Nela, Kortner TROND M. a Augustine ARUKWE. Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator. \textit{Aquatic toxicology}. 2010, roč.~99, č.~2, 10 s. ISSN~0166-445X.
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