| CIBULA, David, M. WIDSCHWENDTER, Ondřej MÁJEK a Ladislav DUŠEK. Tubal ligation and the risk of ovarian cancer: review and meta-analysis. Human Reproduction Update. Oxford: Oxford University Press, 2011, roč. 17, č. 1, s. 55-67. ISSN 1355-4786. Dostupné z: https://dx.doi.org/10.1093/humupd/dmq030. |
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@article{896931,
author = {Cibula, David and Widschwendter, M. and Májek, Ondřej and Dušek, Ladislav},
article_location = {Oxford},
article_number = {1},
doi = {http://dx.doi.org/10.1093/humupd/dmq030},
keywords = {tubal ligation; BRCA mutation; ovarian cancer; meta-analysis},
language = {eng},
issn = {1355-4786},
journal = {Human Reproduction Update},
title = {Tubal ligation and the risk of ovarian cancer: review and meta-analysis},
volume = {17},
year = {2011}
}
TY - JOUR
ID - 896931
AU - Cibula, David - Widschwendter, M. - Májek, Ondřej - Dušek, Ladislav
PY - 2011
TI - Tubal ligation and the risk of ovarian cancer: review and meta-analysis
JF - Human Reproduction Update
VL - 17
IS - 1
SP - 55-67
EP - 55-67
PB - Oxford University Press
SN - 13554786
KW - tubal ligation
KW - BRCA mutation
KW - ovarian cancer
KW - meta-analysis
N2 - background: The reduction of ovarian cancer (OC) risk in women with a history of tubal ligation (TL) has been reported repeatedly, mostly on small populations. We have aimed to provide a critical overview of the studies available to date and to conduct a meta-analysis. results: Meta-analysis of 13 strictly selected studies showed a reduced risk of epithelial OC by 34%. The protective effect of TL was confirmed even in a subgroup of women 10–14 years after the procedure. The risk reduction was confirmed for the endometrioid (RR = 0.40) and serous (RR = 0.73) cancers but not for mucinous. conclusions: The review of relevant articles, as well as the meta-analysis of selected studies, yields consistent data on a significant reduction of OC risk in women who had undergone TL. The results of this meta-analysis should provide an impulse for further research on the etiology of ovarian epithelial cancers, focusing particularly on the importance of retrograde transport of endometrial cells.
ER -
CIBULA, David, M. WIDSCHWENDTER, Ondřej MÁJEK a Ladislav DUŠEK. Tubal ligation and the risk of ovarian cancer: review and meta-analysis. \textit{Human Reproduction Update}. Oxford: Oxford University Press, 2011, roč.~17, č.~1, s.~55-67. ISSN~1355-4786. Dostupné z: https://dx.doi.org/10.1093/humupd/dmq030.
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