Anthracycline therapy and 24-hour blood-pressure profile in
long-term survivors of childhood cancer

J 2010

Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer

NOVÁKOVÁ, Zuzana; Jana ŠŤASTNÁ; Klára HONZÍKOVÁ; Hana HRSTKOVÁ; Nataša HONZÍKOVÁ et al.

Základní údaje

Originální název

Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer

Autoři

NOVÁKOVÁ, Zuzana; Jana ŠŤASTNÁ; Klára HONZÍKOVÁ; Hana HRSTKOVÁ; Nataša HONZÍKOVÁ; Eva ZÁVODNÁ; Bohumil FIŠER a Petr HONZÍK

Vydání

Physiological Research, Praha, Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, 0862-8408

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.646

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/10:00051469

Organizační jednotka

Lékařská fakulta

UT WoS

000279049100014

Klíčová slova anglicky

anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology

Příznaky

Mezinárodní význam

Změněno: 10. 4. 2012 08:56, Mgr. Michal Petr

Anotace

V originále

In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.

Návaznosti

MSM0021622402, záměr

Název: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob

Citovat

NOVÁKOVÁ, Zuzana; Jana ŠŤASTNÁ; Klára HONZÍKOVÁ; Hana HRSTKOVÁ; Nataša HONZÍKOVÁ; Eva ZÁVODNÁ; Bohumil FIŠER a Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. Physiological Research. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, roč. 59, Suppl 1, s. "S97"-S102", 6 s. ISSN 0862-8408.

@article{900493,
   author = {Nováková, Zuzana and Šťastná, Jana and Honzíková, Klára and Hrstková, Hana and Honzíková, Nataša and Závodná, Eva and Fišer, Bohumil and Honzík, Petr},
   article_location = {Praha},
   article_number = {Suppl 1},
   keywords = {anthracyclines; blood pressure; cardiotoxicity; childhood cancer; chronobiology},
   language = {eng},
   issn = {0862-8408},
   journal = {Physiological Research},
   title = {Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer},
   volume = {59},
   year = {2010}
}

TY  - JOUR
ID  - 900493
AU  - Nováková, Zuzana - Šťastná, Jana - Honzíková, Klára - Hrstková, Hana - Honzíková, Nataša - Závodná, Eva - Fišer, Bohumil - Honzík, Petr
PY  - 2010
TI  - Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer
JF  - Physiological Research
VL  - 59
IS  - Suppl 1
SP  - "S97"-S102"
EP  - "S97"-S102"
PB  - Institute of Physiology,Academy of Sciences of the Czech Republic
SN  - 08628408
KW  - anthracyclines
KW  - blood pressure
KW  - cardiotoxicity
KW  - childhood cancer
KW  - chronobiology
N2  - In our previous studies, a decreased blood pressure was reported in children treated by anthracycline (AC). The aim of this study was to assess the long-term effects of AC anticancer therapy in 45 subjects aged 13-22 years by repeated 24-hour Holter monitoring of blood pressure.It is concluded that blood pressure in 19-22 years old AC patients is lower during night hours, the age-dependent increase of blood pressure seen in healthy controls between 13 and 22 years of age does not occur in patients. This finding is consistent with the long-lasting impairment of the sympathetic nervous system caused by anthracyclines.
ER  -

NOVÁKOVÁ, Zuzana; Jana ŠŤASTNÁ; Klára HONZÍKOVÁ; Hana HRSTKOVÁ; Nataša HONZÍKOVÁ; Eva ZÁVODNÁ; Bohumil FIŠER a Petr HONZÍK. Anthracycline therapy and 24-hour blood-pressure profile in long-term survivors of childhood cancer. \textit{Physiological Research}. Praha: Institute of Physiology,Academy of Sciences of the Czech Republic, 2010, roč.~59, Suppl 1, s.~''S97''-S102'', 6 s. ISSN~0862-8408.

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