| BUREŠ, Jan, David ŠMAJS, Jaroslav KVĚTINA, Miroslav FŐRSTL, Jan ŠMARDA, Darina KOHOUTOVÁ, Martin KUNEŠ, Jiří CYRANY, Ilja TACHECÍ, Stanislav REJCHRT, Jiřina LESNÁ, Viktor VOŘÍŠEK a Marcela KOPÁČOVÁ. Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917. Wourld Journal of Gastroenterology. China, roč. 17, č. 5, s. 609-617. ISSN 1007-9327. doi:10.3748/wjg.v17.i5.609. 2011. |
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@article{913361,
author = {Bureš, Jan and Šmajs, David and Květina, Jaroslav and Főrstl, Miroslav and Šmarda, Jan and Kohoutová, Darina and Kuneš, Martin and Cyrany, Jiří and Tachecí, Ilja and Rejchrt, Stanislav and Lesná, Jiřina and Voříšek, Viktor and Kopáčová, Marcela},
article_location = {China},
article_number = {5},
doi = {http://dx.doi.org/10.3748/wjg.v17.i5.609},
keywords = {Bacteriocinogeny; Escherichia coli Nissle 1917; Experimental pigs; Indomethacin},
language = {eng},
issn = {1007-9327},
journal = {Wourld Journal of Gastroenterology},
title = {Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917},
volume = {17},
year = {2011}
}
TY - JOUR
ID - 913361
AU - Bureš, Jan - Šmajs, David - Květina, Jaroslav - Főrstl, Miroslav - Šmarda, Jan - Kohoutová, Darina - Kuneš, Martin - Cyrany, Jiří - Tachecí, Ilja - Rejchrt, Stanislav - Lesná, Jiřina - Voříšek, Viktor - Kopáčová, Marcela
PY - 2011
TI - Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917
JF - Wourld Journal of Gastroenterology
VL - 17
IS - 5
SP - 609-617
EP - 609-617
SN - 10079327
KW - Bacteriocinogeny
KW - Escherichia coli Nissle 1917
KW - Experimental pigs
KW - Indomethacin
N2 - AIM: To evaluate bacteriocinogeny in short-term high-dose indomethacin administration with or without probiotic Escherichia coli Nissle 1917 (EcN) in experimental pigs. METHODS: Twenty-four pigs entered the study: Group A (controls), Group B (probiotics alone), Group C (indomethacin alone) and Group D (probiotics and indomethacin). EcN (3.5x1010 bacteria/d for 14 d) and/or indomethacin (15 mg/kg per day for 10 d) were administrated orally. Anal smears before and smears from the small and large intestine were taken from all animals. Bacteriocin production was determined with 6 different indicator strains. RESULTS: The general microbiota profile was rather uniform in all animals but there was a broad diversity in coliform bacteria (parallel genotypes A, B1, B2 and D found). CONCLUSION: EcN did not exert long-term liveability in the porcine intestine. All experimental pigs remained methanogenic. Indomethacin and EcN administered together might produce the worst impact on bacteriocinogeny.
ER -
BUREŠ, Jan, David ŠMAJS, Jaroslav KVĚTINA, Miroslav F$\backslash$H ORSTL, Jan ŠMARDA, Darina KOHOUTOVÁ, Martin KUNEŠ, Jiří CYRANY, Ilja TACHECÍ, Stanislav REJCHRT, Jiřina LESNÁ, Viktor VOŘÍŠEK a Marcela KOPÁČOVÁ. Bacteriocinogeny in experimental pigs treated with short-term high-dose indomethacin with or without probiotic bacteria Escherichia coli Nissle 1917. \textit{Wourld Journal of Gastroenterology}. China, roč.~17, č.~5, s.~609-617. ISSN~1007-9327. doi:10.3748/wjg.v17.i5.609. 2011.
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