Další formáty:
BibTeX
LaTeX
RIS
@article{923433,
author = {Kiran, S. and Cocco, P. and Mannetje, A. and Satta, G. and D'Andrea, I. and Becker, N. and de Sanjose, S. and Foretová, Lenka and Staines, A. and Kleefeld, S. and Maynadie, M. and Nieters, A. and Brennan, P. and Boffetta, P.},
article_location = {Philadelphia (USA)},
article_number = {6},
doi = {http://dx.doi.org/10.1097/EDE.0b013e3181f4cc0f},
keywords = {CHLOROHYDRIN PRODUCTION; PRODUCTION WORKERS; CANCER-MORTALITY; FOLLOW-UP; COHORT; EPILYMPH; UPDATE},
language = {eng},
issn = {1044-3983},
journal = {Epidemiology},
title = {Occupational exposure to ethylene oxide and risk of lymphoma},
volume = {21},
year = {2010}
}
TY - JOUR
ID - 923433
AU - Kiran, S. - Cocco, P. - Mannetje, A. - Satta, G. - D'Andrea, I. - Becker, N. - de Sanjose, S. - Foretová, Lenka - Staines, A. - Kleefeld, S. - Maynadie, M. - Nieters, A. - Brennan, P. - Boffetta, P.
PY - 2010
TI - Occupational exposure to ethylene oxide and risk of lymphoma
JF - Epidemiology
VL - 21
IS - 6
SP - 905-910
EP - 905-910
PB - Lippincott Williams and Wilkins
SN - 10443983
KW - CHLOROHYDRIN PRODUCTION
KW - PRODUCTION WORKERS
KW - CANCER-MORTALITY
KW - FOLLOW-UP
KW - COHORT
KW - EPILYMPH
KW - UPDATE
N2 - Ethylene oxide, a high-volume commodity, is an established human carcinogen, although the relevant epidemiologic evidence is limited. Methods: We explored the association between occupational exposure to ethylene oxide and risk of lymphoma in a case-control study, including 2347 lymphoma cases first diagnosed in 1998-2004 and 2463 controls, from 6 European countries. The diagnosis of lymphoma was based on the 2001 World Health Organization Classification of lymphoma. Occupational exposure to ethylene oxide was retrospectively assessed by industrial hygienists and occupational physicians based on detailed self-reported information. We modeled risk of lymphoma with unconditional logistic regression analysis as a function of various exposure measures, adjusting for age, sex, and participating center. Results: Thirty-one cases and 27 controls (1.2% of the total study population) were defined as ever having been exposed to ethylene oxide (odds ratio = 1.3 [95% confidence interval [CI] = 0.7-2.1]). Lymphoma risk showed a 4.3-fold increase associated with medium-high frequency of exposure to ethylene oxide (95% CI = 1.4-13). Among major subtypes, chronic lymphocytic leukemia was consistently associated with ethylene oxide exposure, related in a dose-response manner to probability, frequency, and duration of exposure, as well as to cumulative exposure and (less definitively) with exposure intensity.
ER -
KIRAN, S., P. COCCO, A. MANNETJE, G. SATTA, I. D'ANDREA, N. BECKER, S. DE SANJOSE, Lenka FORETOVÁ, A. STAINES, S. KLEEFELD, M. MAYNADIE, A. NIETERS, P. BRENNAN a P. BOFFETTA. Occupational exposure to ethylene oxide and risk of lymphoma. \textit{Epidemiology}. Philadelphia (USA): Lippincott Williams and Wilkins, 2010, roč.~21, č.~6, s.~905-910. ISSN~1044-3983. Dostupné z: https://dx.doi.org/10.1097/EDE.0b013e3181f4cc0f.
|
