| NEČAS, Alois, Ladislav PLÁNKA, Robert SRNEC, Michal CRHA, Jana HLUČILOVÁ, Jiří KLÍMA, David STARÝ, Leoš KŘEN, Evžen AMLER, Lucy VOJTOVÁ, Josef JANČÁŘ a Petr GÁL. Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres. Physiol. Res. Praha: Akademi věd ČR, roč. 59, č. 4, s. 605-614. ISSN 0862-8408. 2010. |
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@article{923548,
author = {Nečas, Alois and Plánka, Ladislav and Srnec, Robert and Crha, Michal and Hlučilová, Jana and Klíma, Jiří and Starý, David and Křen, Leoš and Amler, Evžen and Vojtová, Lucy and Jančář, Josef and Gál, Petr},
article_location = {Praha},
article_number = {4},
keywords = {bone marrow mesenchymal stem cells;allogeneic;micropicking;articular cartilage},
language = {eng},
issn = {0862-8408},
journal = {Physiol. Res.},
title = {Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres},
volume = {59},
year = {2010}
}
TY - JOUR
ID - 923548
AU - Nečas, Alois - Plánka, Ladislav - Srnec, Robert - Crha, Michal - Hlučilová, Jana - Klíma, Jiří - Starý, David - Křen, Leoš - Amler, Evžen - Vojtová, Lucy - Jančář, Josef - Gál, Petr
PY - 2010
TI - Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres
JF - Physiol. Res.
VL - 59
IS - 4
SP - 605-614
EP - 605-614
PB - Akademi věd ČR
SN - 08628408
KW - bone marrow mesenchymal stem cells;allogeneic;micropicking;articular cartilage
N2 - It follows from the above-said that treatment of iatrogenic lesions of the surface of articular cartilage on femur condyles in miniature pigs after transplantation of mesenchymal stem cells in a composite scaffold based on collagen I containing micro- and nanofibers from chitosan resulted in filling of tissue defects in a hyaline type of cartilage. Lesions treated by implantation of scaffold alone or by micropicking were filled with fibrous cartilage with inferior macroscopic, histological and immunohistochemical parameters.
ER -
NEČAS, Alois, Ladislav PLÁNKA, Robert SRNEC, Michal CRHA, Jana HLUČILOVÁ, Jiří KLÍMA, David STARÝ, Leoš KŘEN, Evžen AMLER, Lucy VOJTOVÁ, Josef JANČÁŘ a Petr GÁL. Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and Nanofibres. \textit{Physiol. Res.}. Praha: Akademi věd ČR, roč.~59, č.~4, s.~605-614. ISSN~0862-8408. 2010.
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