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@inproceedings{941067,
author = {Buček, Pavel and Lubal, Přemysl and Netroufalová, Petra and Trnková, Libuše},
address = {Brno},
booktitle = {XI. Pracovní setkání fyzikálních chemiků a elektrochemiků},
editor = {Libuše Trnková},
keywords = {purine based;RNA;DNA;adenine;guanine;aminopurines;acid-based properties;UV-Vis spectroscopy;fluorescence},
language = {eng},
location = {Brno},
isbn = {978-80-7375-514-0},
pages = {59-61},
publisher = {Ediční středisko Mendelu v Brně},
title = {SPECTROPHOTOMETRIC ACID-BASE CHARACTERIZATION OF ADENINE ANALOGUES},
year = {2011}
}
TY - JOUR
ID - 941067
AU - Buček, Pavel - Lubal, Přemysl - Netroufalová, Petra - Trnková, Libuše
PY - 2011
TI - SPECTROPHOTOMETRIC ACID-BASE CHARACTERIZATION OF ADENINE ANALOGUES
PB - Ediční středisko Mendelu v Brně
CY - Brno
SN - 9788073755140
KW - purine based;RNA;DNA;adenine;guanine;aminopurines;acid-based properties;UV-Vis spectroscopy;fluorescence
N2 - Purine based DNA/RNA bases adenine (6-aminopurine) and guanine (2-aminopurin-6- one), serve in live bodies as building blocks of high physiological importance. For in vitro research applications they are replaced by 2-aminopurine and 2,6-diaminopurine. These aminopurines are used either “free” as replacements for adenine/guanine in nucleic acid strands or are subject to further derivatization and use (e.g. enzyme function research [1]). Despite their frequent use, very few is known about the substances’ physico-chemical properties. We studied acid-base properties of 2-aminopurine and 2,6-diaminopurine with use of advanced chemometric tools applied to UV/Vis spectroscopy data and since the 2- aminopurine is highly fluorescent, fluorescence spectroscopy data, too.
ER -
BUČEK, Pavel, Přemysl LUBAL, Petra NETROUFALOVÁ a Libuše TRNKOVÁ. SPECTROPHOTOMETRIC ACID-BASE CHARACTERIZATION OF ADENINE ANALOGUES. In Libuše Trnková. \textit{XI. Pracovní setkání fyzikálních chemiků a elektrochemiků}. Brno: Ediční středisko Mendelu v Brně, 2011, s.~59-61. ISBN~978-80-7375-514-0.
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