2011
Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children
FIAMOLI, Veronika; Jan BLATNÝ; Ondřej ZAPLETAL; Světlana KÖHLEROVÁ; Eva JANOUŠOVÁ et al.Základní údaje
Originální název
Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children
Autoři
Vydání
Thrombosis, Hindawi Publishing Corporation, 2011, 2090-1488
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30200 3.2 Clinical medicine
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/11:00052823
Organizační jednotka
Lékařská fakulta
Klíčová slova anglicky
deep vein thrombosis; LMWH; risk of thrombosis; antiXa
Změněno: 31. 1. 2014 12:44, RNDr. Eva Koriťáková, Ph.D.
Anotace
V originále
Thirty-two consecutive children aged 0–18 years with VTE treated with LMWH administered as a continuous infusion (CI) were identified at the Children’s University Hospital Brno. The treatment led to at least partial resolution of the thrombus within two weeks in 85% of patients. There were no adverse events or increased bleeding reported in any patients. No recurrences were observed during a followup period of 6 months. Although continuous infusion should not replace subcutaneous (SC) administration of LMWH, CI appeared to be safe and efficient and may provide an alternate method of administering LMWH in a subset of the paediatric population where SC administration may not be feasible. Further prospective studies are needed to support the promising findings of our pilot clinical observation.