The role of exercise echocardiography in the diagnostics of
heart failure with normal left ventricular ejection fraction

J 2011

The role of exercise echocardiography in the diagnostics of heart failure with normal left ventricular ejection fraction

MELUZÍN, Jaroslav, Jan SITAR, Jan KŘÍSTEK, Robert PROSECKÝ, Martin PEŠL et. al.

Základní údaje

Originální název

The role of exercise echocardiography in the diagnostics of heart failure with normal left ventricular ejection fraction

Autoři

MELUZÍN, Jaroslav (203 Česká republika, garant, domácí), Jan SITAR (203 Česká republika), Jan KŘÍSTEK (203 Česká republika, domácí), Robert PROSECKÝ (203 Česká republika, domácí), Martin PEŠL (203 Česká republika, domácí), Helena PODROUŽKOVÁ (203 Česká republika, domácí), Vladimír SOŠKA (203 Česká republika, domácí), Roman PANOVSKÝ (203 Česká republika, domácí) a Ladislav DUŠEK (203 Česká republika, domácí)

Vydání

European Journal of Echocardiography, 2011, 1525-2167

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.317

Kód RIV

RIV/00216224:14110/11:00053080

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1093/ejechocard/jer082

UT WoS

000294861700005

Klíčová slova anglicky

Exercise echocardiography; Diastolic heart failure

Příznaky

Mezinárodní význam

Změněno: 23. 3. 2012 13:38, Mgr. Michal Petr

Anotace

V originále

Few data are available on the exercise-induced abnormalities of myocardial function in patients with exertional dyspnoea and normal left ventricular ejection fraction (LV EF). The main aims of this study were to determine the prevalence of isolated exercise-induced heart failure with normal ejection fraction (HFNEF) and to assess whether disturbances in LV or right ventricular longitudinal systolic function are associated with the diagnosis of HFNEF. Eighty-four patients with exertional dyspnoea and normal LV EF and 14 healthy controls underwent spirometry, NT-proBNP plasma analysis, and exercise echocardiography. Doppler LV inflow and tissue mitral and tricuspid annular velocities were analysed at rest and immediately after the termination of exercise. Of the 30 patients with the evidence of HFNEF, 6 (20%) patients had only isolated exercise-induced HFNEF. When compared with the remaining patients, those with HFNEF had a significantly lower resting and exercise peak mitral annular systolic velocity (Sa) and the mitral annular velocity during atrial contraction, lower exercise peak mitral annular velocity at early diastole, and lower exercise peak systolic velocity of tricuspid annular motion. The multivariate logistic regression analysis including both parameters standardly defining HFNEF and the new Doppler variables potentially associated with the diagnosis of HFNEF revealed that NT-proBNP, LV mass index, left atrial volume index, and Sa significantly and independently predict the diagnosis of HFNEF. A significant proportion of patients require exercise to diagnose HFNEF. Sa appears to be a significant independent predictor of HFNEF, which may increase the diagnostic value of models utilizing the variables recommended by the European Society of Cardiology guidelines.

Návaznosti

MSM0021622402, záměr

Název: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob

Citovat

MELUZÍN, Jaroslav, Jan SITAR, Jan KŘÍSTEK, Robert PROSECKÝ, Martin PEŠL, Helena PODROUŽKOVÁ, Vladimír SOŠKA, Roman PANOVSKÝ a Ladislav DUŠEK. The role of exercise echocardiography in the diagnostics of heart failure with normal left ventricular ejection fraction. European Journal of Echocardiography. 2011, roč. 12, č. 8, s. 591–602. ISSN 1525-2167. Dostupné z: https://dx.doi.org/10.1093/ejechocard/jer082.

@article{949985,
   author = {Meluzín, Jaroslav and Sitar, Jan and Křístek, Jan and Prosecký, Robert and Pešl, Martin and Podroužková, Helena and Soška, Vladimír and Panovský, Roman and Dušek, Ladislav},
   article_number = {8},
   doi = {http://dx.doi.org/10.1093/ejechocard/jer082},
   keywords = {Exercise echocardiography; Diastolic heart failure},
   language = {eng},
   issn = {1525-2167},
   journal = {European Journal of Echocardiography},
   title = {The role of exercise echocardiography in the diagnostics of heart failure with normal left ventricular ejection fraction},
   volume = {12},
   year = {2011}
}

TY  - JOUR
ID  - 949985
AU  - Meluzín, Jaroslav - Sitar, Jan - Křístek, Jan - Prosecký, Robert - Pešl, Martin - Podroužková, Helena - Soška, Vladimír - Panovský, Roman - Dušek, Ladislav
PY  - 2011
TI  - The role of exercise echocardiography in the diagnostics of heart failure with normal left ventricular ejection fraction
JF  - European Journal of Echocardiography
VL  - 12
IS  - 8
SP  - 591–602
EP  - 591–602
SN  - 15252167
KW  - Exercise echocardiography
KW  - Diastolic heart failure
N2  - Few data are available on the exercise-induced abnormalities of myocardial function in patients with exertional dyspnoea and normal left ventricular ejection fraction (LV EF). The main aims of this study were to determine the prevalence of isolated exercise-induced heart failure with normal ejection fraction (HFNEF) and to assess whether disturbances in LV or right ventricular longitudinal systolic function are associated with the diagnosis of HFNEF. Eighty-four patients with exertional dyspnoea and normal LV EF and 14 healthy controls underwent spirometry, NT-proBNP plasma analysis, and exercise echocardiography. Doppler LV inflow and tissue mitral and tricuspid annular velocities were analysed at rest and immediately after the termination of exercise. Of the 30 patients with the evidence of HFNEF, 6 (20%) patients had only isolated exercise-induced HFNEF. When compared with the remaining patients, those with HFNEF had a significantly lower resting and exercise peak mitral annular systolic velocity (Sa) and the mitral annular velocity during atrial contraction, lower exercise peak mitral annular velocity at early diastole, and lower exercise peak systolic velocity of tricuspid annular motion. The multivariate logistic regression analysis including both parameters standardly defining HFNEF and the new Doppler variables potentially associated with the diagnosis of HFNEF revealed that NT-proBNP, LV mass index, left atrial volume index, and Sa significantly and independently predict the diagnosis of HFNEF. A significant proportion of patients require exercise to diagnose HFNEF. Sa appears to be a significant independent predictor of HFNEF, which may increase the diagnostic value of models utilizing the variables recommended by the European Society of Cardiology guidelines.
ER  -

MELUZÍN, Jaroslav, Jan SITAR, Jan KŘÍSTEK, Robert PROSECKÝ, Martin PEŠL, Helena PODROUŽKOVÁ, Vladimír SOŠKA, Roman PANOVSKÝ a Ladislav DUŠEK. The role of exercise echocardiography in the diagnostics of heart failure with normal left ventricular ejection fraction. \textit{European Journal of Echocardiography}. 2011, roč.~12, č.~8, s.~591–602. ISSN~1525-2167. Dostupné z: https://dx.doi.org/10.1093/ejechocard/jer082.

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