J 2011

A new approach how to define coefficient of electroactivity of adenine and its twelve derivatives using flow injection analysis with amperometric detection.

ZÍTKA, Ondřej, Helena SKUTKOVA, Vojtěch ADAM, Libuše TRNKOVÁ, Petr BABULA et. al.

Basic information

Original name

A new approach how to define coefficient of electroactivity of adenine and its twelve derivatives using flow injection analysis with amperometric detection.

Authors

ZÍTKA, Ondřej (203 Czech Republic), Helena SKUTKOVA (203 Czech Republic), Vojtěch ADAM (203 Czech Republic), Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution), Petr BABULA (203 Czech Republic), Jaromír HUBÁLEK (203 Czech Republic), Ivo PROVAZNÍK (203 Czech Republic) and René KIZEK (203 Czech Republic, guarantor)

Edition

Electroanalysis, 2011, 1040-0397

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10403 Physical chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.872

RIV identification code

RIV/00216224:14310/11:00053556

Organization unit

Faculty of Science

UT WoS

000292967900007

Keywords in English

Adenine derivatives; Flow injection analysis; Amperometric detection; Glassy carbon electrode; Electroactivity

Tags

Změněno: 12/4/2012 10:53, Ing. Andrea Mikešková

Abstract

V originále

We studied the electrochemical behaviour of adenine derivates (adenosine, 2-aminopurine, 2,6-diaminopurine, 6-benzyl-aminopurine, adenosine monophosphate, cyclic adenosine monophosphate, nicotinamide adenine dinucleotide, adenosine triphosphate, S-adenosyl-L-methionine, and synthetic derivatives AD-3, AD-6 and AD-9) using flow injection analysis with electrochemical detection using a glassy carbon electrode. The influences of pH, flow rate and potential on the signal height of the studied derivates were tested. The optimal pH was 3, the flow rate of the mobile phase 0.75 mLmin(-1) and the potential 1100 mV. Further, we attempted to characterize each of the studied derivatives by mathematical equations and classic analytical parameters. The lowest detection limit was estimated for adenine as 0.9 nM and 2-aminopurine as 0.5 nM.

Links

MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)