| JUŘICA, Jan, Richard BARTEČEK, Eva PINDUROVÁ, Ondřej ZENDULKA, Tomáš KAŠPÁREK a Alexandra ŠULCOVÁ. CYP2D6 phenotyping in clinical practice: serum or urine dextromethorphan/dextrorphan metabolic ratio? In Andrew W. Munro, David Leys. 17th International Conference on Cytochrome P450. Bologna: Medimond, 2011, s. 39-42. ISBN 978-88-7587-616-6. |
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@inproceedings{958892,
author = {Juřica, Jan and Barteček, Richard and Pindurová, Eva and Zendulka, Ondřej and Kašpárek, Tomáš and Šulcová, Alexandra},
address = {Bologna},
booktitle = {17th International Conference on Cytochrome P450},
editor = {Andrew W. Munro, David Leys},
keywords = {CYP2D6; phenotype},
language = {eng},
location = {Bologna},
isbn = {978-88-7587-616-6},
pages = {39-42},
publisher = {Medimond},
title = {CYP2D6 phenotyping in clinical practice: serum or urine dextromethorphan/dextrorphan metabolic ratio?},
year = {2011}
}
TY - JOUR
ID - 958892
AU - Juřica, Jan - Barteček, Richard - Pindurová, Eva - Zendulka, Ondřej - Kašpárek, Tomáš - Šulcová, Alexandra
PY - 2011
TI - CYP2D6 phenotyping in clinical practice: serum or urine dextromethorphan/dextrorphan metabolic ratio?
PB - Medimond
CY - Bologna
SN - 9788875876166
KW - CYP2D6
KW - phenotype
N2 - The aim of this work was to elucidate if CYP2D6 phenotyping by evaluation of molar dextromethorphan to dextrorphan metabolic ratio (MRDEM/DOR) in serum has the usability and reliability as the assessment of MRDEM/DOR in urine. We measured MRDEM/DOR in serum and CYP2D6 genotype in 51 drug-naive patients and investigated cut-off value for discrimination of poor metabolizers from extensive and intermediate ones. The correlation of serum MRDEM/DOR with urine MRDEM/DOR in 30 healthy volunteers was analysed in parallel.
ER -
JUŘICA, Jan, Richard BARTEČEK, Eva PINDUROVÁ, Ondřej ZENDULKA, Tomáš KAŠPÁREK a Alexandra ŠULCOVÁ. CYP2D6 phenotyping in clinical practice: serum or urine dextromethorphan/dextrorphan metabolic ratio? In Andrew W. Munro, David Leys. \textit{17th International Conference on Cytochrome P450}. Bologna: Medimond, 2011, s.~39-42. ISBN~978-88-7587-616-6.
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