ABC transporters affect the detection of intracellular oxidants
by fluorescent probes.

J 2011

ABC transporters affect the detection of intracellular oxidants by fluorescent probes.

PROCHÁZKOVÁ, Jiřina; Lukáš KUBALA; Hana KOTASOVÁ; Iva GUDERNOVÁ; Zuzana ŠRÁMKOVÁ et al.

Základní údaje

Originální název

ABC transporters affect the detection of intracellular oxidants by fluorescent probes.

Autoři

PROCHÁZKOVÁ, Jiřina; Lukáš KUBALA; Hana KOTASOVÁ; Iva GUDERNOVÁ; Zuzana ŠRÁMKOVÁ; Michaela PEKAROVÁ; Balazs SARKADI a Jiří PACHERNÍK

Vydání

Free Radical Res. 2011, 1071-5762

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.878

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/11:00050241

Organizační jednotka

Přírodovědecká fakulta

DOI

https://doi.org/10.3109/10715762.2011.579120

UT WoS

000291222100004

Klíčová slova anglicky

Fluorescence; redox status; mitochondria; reactive oxygen species (ROS)

Štítky

AKR, rivok

Změněno: 20. 4. 2012 11:41, Ing. Andrea Mikešková

Anotace

V originále

Intracellular production of reactive oxygen species (ROS) plays an important role in the control of cell physiology. For the assessment of intracellular ROS production, a plethora of fluorescent probes is commonly used. Interestingly, chemical structures of these probes imply they could be substrates of plasma membrane efflux pumps, called ABC transporters. This study tested whether the determination of intracellular ROS production and mitochondrial membrane potential by selected fluorescent probes is modulated by the expression and activity of ABC transporters.

Návaznosti

GA301/08/0717, projekt VaV

Název: Regulace diferenciace ES buněk prostřednictvím receptoru gp130

Investor: Grantová agentura ČR, Regulace diferenciace ES buněk prostřednictvím receptoru gp130

Citovat

PROCHÁZKOVÁ, Jiřina; Lukáš KUBALA; Hana KOTASOVÁ; Iva GUDERNOVÁ; Zuzana ŠRÁMKOVÁ; Michaela PEKAROVÁ; Balazs SARKADI a Jiří PACHERNÍK. ABC transporters affect the detection of intracellular oxidants by fluorescent probes. Free Radical Res. 2011, roč. 45, č. 7, s. 779-787. ISSN 1071-5762. Dostupné z: https://doi.org/10.3109/10715762.2011.579120.

@article{962368,
   author = {Procházková, Jiřina and Kubala, Lukáš and Kotasová, Hana and Gudernová, Iva and Šrámková, Zuzana and Pekarová, Michaela and Sarkadi, Balazs and Pacherník, Jiří},
   article_number = {7},
   doi = {https://doi.org/10.3109/10715762.2011.579120},
   keywords = {Fluorescence; redox status; mitochondria; reactive oxygen species (ROS)},
   language = {eng},
   issn = {1071-5762},
   journal = {Free Radical Res.},
   title = {ABC transporters affect the detection of intracellular oxidants by fluorescent probes.},
   volume = {45},
   year = {2011}
}

TY  - JOUR
ID  - 962368
AU  - Procházková, Jiřina - Kubala, Lukáš - Kotasová, Hana - Gudernová, Iva - Šrámková, Zuzana - Pekarová, Michaela - Sarkadi, Balazs - Pacherník, Jiří
PY  - 2011
TI  - ABC transporters affect the detection of intracellular oxidants by fluorescent probes.
JF  - Free Radical Res.
VL  - 45
IS  - 7
SP  - 779-787
EP  - 779-787
SN  - 10715762
KW  - Fluorescence
KW  - redox status
KW  - mitochondria
KW  - reactive oxygen species (ROS)
N2  - Intracellular production of reactive oxygen species (ROS) plays an important role in the control of cell physiology. For the assessment of intracellular ROS production, a plethora of fluorescent probes is commonly used. Interestingly, chemical structures of these probes imply they could be substrates of plasma membrane efflux pumps, called ABC transporters. This study tested whether the determination of intracellular ROS production and mitochondrial membrane potential by selected fluorescent probes is modulated by the expression and activity of ABC transporters.
ER  -

PROCHÁZKOVÁ, Jiřina; Lukáš KUBALA; Hana KOTASOVÁ; Iva GUDERNOVÁ; Zuzana ŠRÁMKOVÁ; Michaela PEKAROVÁ; Balazs SARKADI a Jiří PACHERNÍK. ABC transporters affect the detection of intracellular oxidants by fluorescent probes. \textit{Free Radical Res.}. 2011, roč.~45, č.~7, s.~779-787. ISSN~1071-5762. Dostupné z: https://doi.org/10.3109/10715762.2011.579120.

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