Optical Detection of Protein Adsorption on Doped Titanium
Surface

C 2011

Optical Detection of Protein Adsorption on Doped Titanium Surface

SILVENNOINEN, Raimo; Niko PENTTINEN; Martti SILVENNOINEN; Stanislav HASOŇ; Vladimír VETTERL et al.

Základní údaje

Originální název

Optical Detection of Protein Adsorption on Doped Titanium Surface

Autoři

SILVENNOINEN, Raimo; Niko PENTTINEN; Martti SILVENNOINEN; Stanislav HASOŇ; Vladimír VETTERL; Sonia BARTÁKOVÁ; Patrik PRACHÁR; Jiří VANĚK a Vítězslav BŘEZINA

Vydání

Croatia, Biomaterials Science and Engineering, od s. 173-190, 18 s. Biomaterial Science and Engeneering, 2011

Nakladatel

InTech open beta

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Chorvatsko

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/11:00054869

Organizační jednotka

Lékařská fakulta

ISBN

978-953-307-609-6

Klíčová slova česky

optická detekce; implantát;absorpce

Klíčová slova anglicky

optical detection; implant;absorption

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 2. 2012 13:14, Mgr. Michal Petr

Anotace

V originále

The frequently used biomaterial in hard tissue replacement, such as dental and orthopaedic implants, is titanium. (Ball et al., 1996; Höök et al., 2002a; Huang et al., 2003; Imamura et al., 2008; Jones et al., 2000; Walivaara et al., 1994; Yang et al., 2003) These kind of biomaterial applications made of titanium are satisfactory products, because of their ability to adsorb certain proteins. After implantation, within a few seconds, the biomaterial surface becomes coated with a film of adsorbed proteins mediating the interaction between the implant and the body environment. Since an implant is exposed to blood during implantation, the initial protein layer is mainly composed of plasma proteins. Human plasma fibrinogen (HPF) is the relevant protein, which adsorbs on biomaterial surfaces. HPF partakes in blood coagulation, facilitates adhesion and aggregation of platelets (Cacciafesta et al., 2001; 2000). The structure and composition of the adsorbed protein layer determine the type and extent of the subsequent biological reactions, such as activation of coagulation and immune response and osseointegration (Nygren et al., 1997). Thus, the initially adsorbed protein layer is a factor determining the biocompatibility , and also in recent years interest has been focused to preparation of hydrocarbons doped with Ti and used different methods to analyzing of biocompatibility for important proteins . The production and application of doped titanium surfaces are under intensive research, and the results have shown the positive views on the adaptation of these materials as a biomaterial, as equal or even better than the bulk titanium. The doping of titanium is performed typically by inserting impurities like N, Nb, Zr, Ta, Al, Cr and V.

Návaznosti

1M0528, projekt VaV

Název: Stomatologické výzkumné centrum

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Stomatologické výzkumné centrum

Citovat

SILVENNOINEN, Raimo; Niko PENTTINEN; Martti SILVENNOINEN; Stanislav HASOŇ; Vladimír VETTERL; Sonia BARTÁKOVÁ; Patrik PRACHÁR; Jiří VANĚK a Vítězslav BŘEZINA. Optical Detection of Protein Adsorption on Doped Titanium Surface. In Biomaterials Science and Engineering. Croatia: InTech open beta, 2011, s. 173-190. Biomaterial Science and Engeneering. ISBN 978-953-307-609-6.

@inbook{965952,
   author = {Silvennoinen, Raimo and Penttinen, Niko and Silvennoinen, Martti and Hasoň, Stanislav and Vetterl, Vladimír and Bartáková, Sonia and Prachár, Patrik and Vaněk, Jiří and Březina, Vítězslav},
   address = {Croatia},
   booktitle = {Biomaterials Science and Engineering},
   keywords = {optical detection; implant;absorption},
   language = {eng},
   location = {Croatia},
   isbn = {978-953-307-609-6},
   pages = {173-190},
   publisher = {InTech open beta},
   title = {Optical Detection of Protein Adsorption on Doped Titanium Surface},
   year = {2011}
}

TY  - CHAP
ID  - 965952
AU  - Silvennoinen, Raimo - Penttinen, Niko - Silvennoinen, Martti - Hasoň, Stanislav - Vetterl, Vladimír - Bartáková, Sonia - Prachár, Patrik - Vaněk, Jiří - Březina, Vítězslav
PY  - 2011
TI  - Optical Detection of Protein Adsorption on Doped Titanium Surface
VL  - Biomaterial Science and Engeneering
PB  - InTech open beta
CY  - Croatia
SN  - 9789533076096
KW  - optical detection
KW  - implant;absorption
N2  - The frequently used biomaterial in hard tissue replacement, such as dental and orthopaedic implants, is titanium. (Ball et al., 1996; Höök et al., 2002a; Huang et al., 2003; Imamura et al., 2008; Jones et al., 2000; Walivaara et al., 1994; Yang et al., 2003) These kind of biomaterial applications made of titanium are satisfactory products, because of their ability to adsorb certain proteins. After implantation, within a few seconds, the biomaterial surface becomes coated with a film of adsorbed proteins mediating the interaction between the implant and the body environment. Since an implant is exposed to blood during implantation, the initial protein layer is mainly composed of plasma proteins. Human plasma fibrinogen (HPF) is the relevant protein, which adsorbs on biomaterial surfaces. HPF partakes in blood coagulation, facilitates adhesion and aggregation of platelets (Cacciafesta et al., 2001; 2000). The structure and composition of the adsorbed protein layer determine the type and extent of the subsequent biological reactions, such as activation of coagulation and immune response and osseointegration (Nygren et al., 1997). Thus, the initially adsorbed protein layer is a factor determining the biocompatibility , and also in recent years interest has been focused to preparation of hydrocarbons doped with Ti and used different methods to analyzing of biocompatibility for important proteins . The production and application of doped titanium surfaces are under intensive research, and the results have shown the positive views on the adaptation of these materials as a biomaterial, as equal or even better than the bulk titanium. The doping of titanium is performed typically by inserting impurities like N, Nb, Zr, Ta, Al, Cr and V.
ER  -

SILVENNOINEN, Raimo; Niko PENTTINEN; Martti SILVENNOINEN; Stanislav HASOŇ; Vladimír VETTERL; Sonia BARTÁKOVÁ; Patrik PRACHÁR; Jiří VANĚK a Vítězslav BŘEZINA. Optical Detection of Protein Adsorption on Doped Titanium Surface. In \textit{Biomaterials Science and Engineering}. Croatia: InTech open beta, 2011, s.~173-190. Biomaterial Science and Engeneering. ISBN~978-953-307-609-6.

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