Hippocampal P300 recorded during a simple auditory reaction
time task (intracerebral study).

a 2011

Hippocampal P300 recorded during a simple auditory reaction time task (intracerebral study).

ROMAN, Robert; Jan CHLÁDEK; Milan BRÁZDIL; Ivan REKTOR; Pavel JURÁK et al.

Základní údaje

Originální název

Hippocampal P300 recorded during a simple auditory reaction time task (intracerebral study).

Autoři

ROMAN, Robert ; Jan CHLÁDEK; Milan BRÁZDIL; Ivan REKTOR; Pavel JURÁK a Miloslav KUKLETA

Vydání

XI International Conference on Cognitive Neuroscience (ICON XI). Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011. 2011

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Označené pro přenos do RIV

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.3389/2011.207.00059

Klíčová slova česky

Intrakraniální elektrofyziologie, p300

Klíčová slova anglicky

Intra-cranial Electrophysiology, p300

Změněno: 5. 3. 2017 07:33, doc. MUDr. Robert Roman, Ph.D.

Anotace

V originále

This paper attempts to make possible time relationship of hippocampal P300, evoked by 1 kHz tone during a simple sensorimotor task, to stimulus or motor response. In 9 patients with medically intractable epilepsies, depth electrodes were implanted to localize the seizure origin prior to surgical treatment. 19 of 70 electrodes were targeted into the hippocampus. Each subject was instructed to respond to the 1 kHz tone by pressing a button in the dominant hand. P300 components recorded in the hippocampus were analyzed both in stimulus-locked and response-locked averages, which were separately averaged for fast and slow responses. Local generation of hippocampal P300 was demonstrated in all 19 electrodes. The mean latency was 415 ms (SD=58 ms), the mean amplitude was 108 mV (SD=87 mV). Three different types of time relationships of hippocampal P300 were found: 1) time-locked to the stimulus - in 12 cases/6 patients; 2) time-locked to the motor response - in 2 cases/1 patient; and 3) ambiguous time relationship to stimulus and motor response - in 5 cases/3 patients. The three types of relationships were found in both left and right hemispheres. Our results show that the hippocampus in all the patients evoked a response during a simple sensorimotor task. The finding of the three different types of time relationships to stimulus and to motor response is in accordance with the results we obtained during visual oddball task. It may suggest that at least certain parts of this structure are involved in simple sensorimotor tasks in all steps of information processing

Návaznosti

GAP103/11/0933, projekt VaV

Název: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Investor: Grantová agentura ČR, Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

ROMAN, Robert; Jan CHLÁDEK; Milan BRÁZDIL; Ivan REKTOR; Pavel JURÁK a Miloslav KUKLETA. Hippocampal P300 recorded during a simple auditory reaction time task (intracerebral study). In XI International Conference on Cognitive Neuroscience (ICON XI). Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011. 2011. Dostupné z: https://doi.org/10.3389/2011.207.00059.

@proceedings{968898,
   author = {Roman, Robert and Chládek, Jan and Brázdil, Milan and Rektor, Ivan and Jurák, Pavel and Kukleta, Miloslav},
   booktitle = {XI International Conference on Cognitive Neuroscience (ICON XI). Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011.},
   doi = {https://doi.org/10.3389/2011.207.00059},
   keywords = {Intra-cranial Electrophysiology, p300},
   language = {eng},
   title = {Hippocampal P300 recorded during a simple auditory reaction time task (intracerebral study).},
   year = {2011}
}

TY  - CONF
ID  - 968898
AU  - Roman, Robert - Chládek, Jan - Brázdil, Milan - Rektor, Ivan - Jurák, Pavel - Kukleta, Miloslav
PY  - 2011
TI  - Hippocampal P300 recorded during a simple auditory reaction time task (intracerebral study).
KW  - Intra-cranial Electrophysiology, p300
N2  - This paper attempts to make possible time relationship of hippocampal P300, evoked by 1 kHz tone during a simple sensorimotor task, to stimulus or motor response. In 9 patients with medically intractable epilepsies, depth electrodes were implanted to localize the seizure origin prior to surgical treatment. 19 of 70 electrodes were targeted into the hippocampus. Each subject was instructed to respond to the 1 kHz tone by pressing a button in the dominant hand. P300 components recorded in the hippocampus were analyzed both in stimulus-locked and response-locked averages, which were separately averaged for fast and slow responses. Local generation of hippocampal P300 was demonstrated in all 19 electrodes. The mean latency was 415 ms (SD=58 ms), the mean amplitude was 108 mV (SD=87 mV). Three different types of time relationships of hippocampal P300 were found: 1) time-locked to the stimulus - in 12 cases/6 patients; 2) time-locked to the motor response - in 2 cases/1 patient; and 3) ambiguous time relationship to stimulus and motor response - in 5 cases/3 patients. The three types of relationships were found in both left and right hemispheres. Our results show that the hippocampus in all the patients evoked a response during a simple sensorimotor task. The finding of the three different types of time relationships to stimulus and to motor response is in accordance with the results we obtained during visual oddball task. It may suggest that at least certain parts of this structure are involved in simple sensorimotor tasks in all steps of information processing
ER  -

ROMAN, Robert; Jan CHLÁDEK; Milan BRÁZDIL; Ivan REKTOR; Pavel JURÁK a Miloslav KUKLETA. Hippocampal P300 recorded during a simple auditory reaction time task (intracerebral study). In \textit{XI International Conference on Cognitive Neuroscience (ICON XI). Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011.}. 2011. Dostupné z: https://doi.org/10.3389/2011.207.00059.

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