| BENAVENTE, Y., G. MBISA, N. LABO, D. CASABONNE, N. BECKER, M. MAYNADIE, Lenka FORETOVÁ, Pierluigi COCCO, A. NIETERS, A. STAINES, P. BOFETTA, P. BRENNAN, D. WHITBY a S. DE SANJOSE. Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study. British Journal of Cancer. England: Nature Publishing Group, 2011, roč. 105, č. 11, s. 1768-1771. ISSN 0007-0920. Dostupné z: https://dx.doi.org/10.1038/bjc.2011.392. |
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@article{969148,
author = {Benavente, Y. and Mbisa, G. and Labo, N. and Casabonne, D. and Becker, N. and Maynadie, M. and Foretová, Lenka and Cocco, Pierluigi and Nieters, A. and Staines, A. and Bofetta, P. and Brennan, P. and Whitby, D. and de Sanjose, S.},
article_location = {England},
article_number = {11},
doi = {http://dx.doi.org/10.1038/bjc.2011.392},
keywords = {epidemiology; Kaposi's sarcoma-associated herpes virus; human herpes virus 8; serology; lymphoma},
language = {eng},
issn = {0007-0920},
journal = {British Journal of Cancer},
title = {Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study},
volume = {105},
year = {2011}
}
TY - JOUR
ID - 969148
AU - Benavente, Y. - Mbisa, G. - Labo, N. - Casabonne, D. - Becker, N. - Maynadie, M. - Foretová, Lenka - Cocco, Pierluigi - Nieters, A. - Staines, A. - Bofetta, P. - Brennan, P. - Whitby, D. - de Sanjose, S.
PY - 2011
TI - Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study
JF - British Journal of Cancer
VL - 105
IS - 11
SP - 1768-1771
EP - 1768-1771
PB - Nature Publishing Group
SN - 00070920
KW - epidemiology
KW - Kaposi's sarcoma-associated herpes virus
KW - human herpes virus 8
KW - serology
KW - lymphoma
N2 - Kaposi's sarcoma-associated herpes virus is associated with primary effusion lymphoma and multicentric Castleman's disease. METHODS: Seropositivity to lytic and latent Kaposi's sarcoma herpes virus (KSHV) antigens were examined in 2083 lymphomas and 2013 controls from six European countries. RESULTS: Antibodies against KSHV latent and lytic antigens were detectable in 4.5% and 3.4% of controls, respectively, and 3.6% of cases (P>0.05). The KSHV seropositivity was associated with splenic marginal zone lymphoma (SMZL) (odds ratio (OR) = 4.11, 95% confidence interval (CI) 1.57-10.83) and multiple myeloma (OR = 0.31, 95% CI = 0.11-0.85). CONCLUSION: The KSHV is unlikely to contribute importantly to lymphomagenesis among immunocompetent subjects. However, the observed association with SMZL may underline a chronic antigen mechanism in its aetiology.
ER -
BENAVENTE, Y., G. MBISA, N. LABO, D. CASABONNE, N. BECKER, M. MAYNADIE, Lenka FORETOVÁ, Pierluigi COCCO, A. NIETERS, A. STAINES, P. BOFETTA, P. BRENNAN, D. WHITBY a S. DE SANJOSE. Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study. \textit{British Journal of Cancer}. England: Nature Publishing Group, 2011, roč.~105, č.~11, s.~1768-1771. ISSN~0007-0920. Dostupné z: https://dx.doi.org/10.1038/bjc.2011.392.
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