RAŠOVSKÁ, Hana a Irena REKTOROVÁ. Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study. Journal of the Neurological Sciences, 2011, roč. 310, 1-2, s. 279–282. ISSN 0022-510X. doi:10.1016/j.jns.2011.07.048.
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Základní údaje
Originální název Instrumental activities of daily living in Parkinson's disease dementia as compared with Alzheimer's disease: Relationship to motor disability and cognitive deficits: A pilot study
Autoři RAŠOVSKÁ, Hana (203 Česká republika, garant, domácí) a Irena REKTOROVÁ (203 Česká republika, domácí).
Vydání Journal of the Neurological Sciences, 2011, 0022-510X.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 3. Medical and Health Sciences
Stát vydavatele Nizozemsko
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 2.353
Kód RIV RIV/00216224:14110/11:00055892
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1016/j.jns.2011.07.048
UT WoS 000296927500061
Klíčová slova anglicky Parkinsons disease dementia; Alzheimers disease; Instrumental activities of daily living; Extrapyramidal symptoms; Cognitive functions
Příznaky Mezinárodní význam
Změnil Změnil: Mgr. Michal Petr, učo 65024. Změněno: 1. 3. 2012 11:47.
Anotace
Our objective was to assess which clinical factors contribute most to the impairment of instrumental activities of daily living (IADL) in patients with dementia in Parkinsons disease (PDD) as compared to age- and dementia duration-matched patients with Alzheimer's disease (AD). Methods: Eighteen consecutive subjects (16 men, 2 women) with PDD and 30 age- and dementia duration-matched subjects with AD (13 men, 17 women) were recruited. The groups were not matched for their Mini-Mental Status Examination (MMSE) score. Neuropsychiatric, cognitive and motor data were collected in a routine clinical setting using the MMSE, four brief tests of the seven minute screen (i.e. the Benton Temporal Orientation, Grober and Buschkes enhanced cued recall, verbal fluency, and the clock drawing test), the Neuropsychiatric Inventory, a modified version of the Hoehn and Yahr scale and a Czech modified version of Lawton's IADL questionnaire. The IADL scores were correlated with clinical variables in each group. Results: There were no differences in IADL abilities between both groups. A significant association was found between IADL and cognitive impairment as measured by screening tests in the AD group. In the PDD group, IADL scores were particularly correlated with PD duration (r = -0.73, p<0.01) and the Hoehn and Yahr score (r = -0.59, p<0.01). Conclusion: Our pilot study results show that motor deficits remain the major contributor to IADL impairment in PDD.
Návaznosti
MSM0021622404, záměrNázev: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Výzkumné záměry
VytisknoutZobrazeno: 15. 10. 2019 06:10