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@article{981075,
author = {Hnatkova, Katerina and Toman, Ondřej and Šišáková, Martina and Novotný, Tomáš and Malik, Marek},
article_number = {6},
doi = {http://dx.doi.org/10.1016/j.jelectrocard.2010.06.003},
keywords = {T-WAVE MORPHOLOGY; PREDICTS CARDIAC DEATH; LONG QT SYNDROME; HEART-RATE; ELECTROCARDIOGRAPHIC QT; GENERAL-POPULATION; INTERVALS; ANGLE; VARIABILITY; DISEASE},
language = {eng},
issn = {0022-0736},
journal = {JOURNAL OF ELECTROCARDIOLOGY},
note = {35th Annual Conference of the International-Society-for-Computerized-Electrocardiology},
title = {Dynamic properties of selected repolarization descriptors},
volume = {43},
year = {2010}
}
TY - JOUR
ID - 981075
AU - Hnatkova, Katerina - Toman, Ondřej - Šišáková, Martina - Novotný, Tomáš - Malik, Marek
PY - 2010
TI - Dynamic properties of selected repolarization descriptors
JF - JOURNAL OF ELECTROCARDIOLOGY
VL - 43
IS - 6
SP - 588-594
EP - 588-594
SN - 00220736
N1 - 35th Annual Conference of the International-Society-for-Computerized-Electrocardiology
KW - T-WAVE MORPHOLOGY
KW - PREDICTS CARDIAC DEATH
KW - LONG QT SYNDROME
KW - HEART-RATE
KW - ELECTROCARDIOGRAPHIC QT
KW - GENERAL-POPULATION
KW - INTERVALS
KW - ANGLE
KW - VARIABILITY
KW - DISEASE
N2 - A number of morphological indices have been proposed to characterize electrocardiographic patterns of ventricular repolarization mostly studying spatial and temporal patterns of T waves. Comparisons between different clinical populations exist but data on the suitability of the T-wave descriptors to characterize and quantify physiologic regulations of ventricular repolarization are lacking. To initiate such investigations, a study was conducted comparing the influence of provoked heart rate changes on the duration of QT interval, the roundness of T wave loop expressed by the relative T wave area, and on the 3-dimensional QRS-T angle. A population of 40 healthy subjects (18 women, mean age 30.4 +/- 8.1 years) was studied. In each subject, provocative tests involving changes from strict supine to unsupported sitting and to unsupported standing positions were repeated twice during each of 3 separate monitoring days. Continuous 12-lead electrocardiograms were obtained during the provocative tests. The speed of the adaptation of the repolarization descriptors to heart rate changes was characterized by lambda parameters of previously published exponential decay model of R-R interval related hysteresis. The comparisons showed that the adaptation of QT interval to heart rate changes was much slower than that of the investigated T-wave morphological descriptors: the mean (SD) values of lambda parameters were 5.01 +/- 1.13, 12.72 +/- 8.66, and 12.90 +/- 11.37 for QT interval, QRS-T angle, and relative T-wave area, respectively (P < .001 for the difference between QT interval and both morphological descriptors). The study suggests that the different numerical quantifiers of vertricular repolarization that may be derived from standard electrocardiographic tracings likely represent separate and distinct physiologic entities.
ER -
HNATKOVA, Katerina, Ondřej TOMAN, Martina ŠIŠÁKOVÁ, Tomáš NOVOTNÝ a Marek MALIK. Dynamic properties of selected repolarization descriptors. \textit{JOURNAL OF ELECTROCARDIOLOGY}. 2010, roč.~43, č.~6, s.~588-594. ISSN~0022-0736. Dostupné z: https://dx.doi.org/10.1016/j.jelectrocard.2010.06.003.
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