MicroRNAs and their target gene networks in renal cell
carcinoma

J 2011

MicroRNAs and their target gene networks in renal cell carcinoma

RÉDOVÁ, Martina, Marek SVOBODA and Ondřej SLABÝ

Basic information

Original name

MicroRNAs and their target gene networks in renal cell carcinoma

Authors

RÉDOVÁ, Martina (203 Czech Republic), Marek SVOBODA (203 Czech Republic) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Biochem Biophys Res Commun, San Diego, Elsevier Science, 2011, 0006-291X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.484

RIV identification code

RIV/00216224:14740/11:00060083

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1016/j.bbrc.2011.01.019

UT WoS

000287627500001

Keywords in English

MicroRNA; Renal cell carcinoma; Hypoxia; Epithelial-mesenchymal transition; Proliferation; Apoptosis

Abstract

V originále

MiRNAs are related to the processes of cell proliferation, apoptosis, angiogenesis, invasion, and metastasis in RCC. MiRNAs expression profiles are associated with several RCC-specific genetic alterations. It has been well documented that several miRNAs are downstream effector molecules of the HIF-induced hypoxia response. MiR-200 family is linked to epithelial-mesenchymal transition which is one of the most significant pathogenetic mechanism in RCC. Mechanistic studies in RCC have provided the rationale of using miRNAs as potential therapeutic targets.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

Citovat

RÉDOVÁ, Martina, Marek SVOBODA and Ondřej SLABÝ. MicroRNAs and their target gene networks in renal cell carcinoma. Biochem Biophys Res Commun. San Diego: Elsevier Science, 2011, vol. 405, No 2, p. 153-156. ISSN 0006-291X. Available from: https://dx.doi.org/10.1016/j.bbrc.2011.01.019.

@article{984074,
   author = {Rédová, Martina and Svoboda, Marek and Slabý, Ondřej},
   article_location = {San Diego},
   article_number = {2},
   doi = {http://dx.doi.org/10.1016/j.bbrc.2011.01.019},
   keywords = {MicroRNA; Renal cell carcinoma; Hypoxia; Epithelial-mesenchymal transition; Proliferation; Apoptosis},
   language = {eng},
   issn = {0006-291X},
   journal = {Biochem Biophys Res Commun},
   title = {MicroRNAs and their target gene networks in renal cell carcinoma},
   url = {http://www.sciencedirect.com/science/article/pii/S0006291X11000386},
   volume = {405},
   year = {2011}
}

TY  - JOUR
ID  - 984074
AU  - Rédová, Martina - Svoboda, Marek - Slabý, Ondřej
PY  - 2011
TI  - MicroRNAs and their target gene networks in renal cell carcinoma
JF  - Biochem Biophys Res Commun
VL  - 405
IS  - 2
SP  - 153-156
EP  - 153-156
PB  - Elsevier Science
SN  - 0006291X
KW  - MicroRNA
KW  - Renal cell carcinoma
KW  - Hypoxia
KW  - Epithelial-mesenchymal transition
KW  - Proliferation
KW  - Apoptosis
UR  - http://www.sciencedirect.com/science/article/pii/S0006291X11000386
L2  - http://www.sciencedirect.com/science/article/pii/S0006291X11000386
N2  - MiRNAs are related to the processes of cell proliferation, apoptosis, angiogenesis, invasion, and metastasis in RCC. MiRNAs expression profiles are associated with several RCC-specific genetic alterations. It has been well documented that several miRNAs are downstream effector molecules of the HIF-induced hypoxia response. MiR-200 family is linked to epithelial-mesenchymal transition which is one of the most significant pathogenetic mechanism in RCC. Mechanistic studies in RCC have provided the rationale of using miRNAs as potential therapeutic targets.
ER  -

RÉDOVÁ, Martina, Marek SVOBODA and Ondřej SLABÝ. MicroRNAs and their target gene networks in renal cell carcinoma. \textit{Biochem Biophys Res Commun}. San Diego: Elsevier Science, 2011, vol.~405, No~2, p.~153-156. ISSN~0006-291X. Available from: https://dx.doi.org/10.1016/j.bbrc.2011.01.019.

Detailed Information on Publication Record