2012
Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour
BIENERTOVÁ VAŠKŮ, Julie a Petr BIENERTZákladní údaje
Originální název
Adipokines as an Important Factor Related to the Prenatal Programming of Nutritional Behaviour
Autoři
Vydání
New York, Advances in Medicine and Biology : Volume 43, od s. 263-272, 10 s. Advances in Medicine and Biology, 2012
Nakladatel
Nova Science Publishers
Další údaje
Jazyk
angličtina
Typ výsledku
Kapitola resp. kapitoly v odborné knize
Obor
30000 3. Medical and Health Sciences
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Forma vydání
tištěná verze "print"
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/12:00060426
Organizační jednotka
Lékařská fakulta
ISBN
978-1-62100-843-9
Klíčová slova anglicky
adipokines; fetal modelling; epigenetics
Změněno: 10. 4. 2013 15:56, Ing. Mgr. Věra Pospíšilíková
V originále
It has been suggested previously that some of the obesity-associated behavioral patterns as well as metabolic pathways are “programmed” during fetal development. The concept of “developmental metabolic programming” is based on the hypothesis that nutritional as well as metabolic status of the mother during the pregnancy affects the metabolism control in the child, thus resulting in a unique phenotype allowing for better adaptation of the infant to the environmental conditions. However, very little is known about factors that are responsible for this programming. The products of the white adipose tissue, so called adipokines, could be elegant candidates for controlling the process of fetal programming as they mostly correlated with the total fat mass and have pleiotropic effects both at parakrine and endocrine levels. It has been reported recently that e.g. leptin, adiponectin, resistin and visfatin as well as numerous other adipokines are associated with specific nutritional or metabolic conditions resulting in a wide range of adaptive phenotypes across the population. Moreover, placenta has been identified as a major source of adipokines, which also lead to the recognition of prenatal period as a highly specific, unique metabolic state resulting in specific feeding and metabolic patterns of the infant. This review covers the major aspects of adipokines in relation to prenatal fetal modelling of the nutritional behaviour.
Česky
Kapitola je přehledem úlohy jednotlivých adipokinů u fetálního modelování.