The main aim of this thesis is to provide a cultural analysis of Vladimir Nabokov’s famous novel Lolita. Since the book was first published in 1955, it has not only attracted many readers, but also a number of artists creating their works in various fields of art. The work quickly began to serve as an inspiration for various adaptations and appropriations. The main aim of this thesis is to focus on the contemporary appropriations of Lolita created in the 21st century. The thesis is introduced by a theoretical background presenting the thoughts and theories of several scholars from the field of adaptation, appropriation, reception studies, and mythology such as Linda Hutcheon, Julie Sanders, Janet Staiger, and Claude Lévi-Strauss. Then before the thesis moves to its main body, the next chapter briefly introduces both film adaptation of Lolita, which are further referenced in the next chapters. The works encompassed in the main body of the thesis are divided into three main chapters according to the media that they are appropriated in as well as the mode of engagement that they use. First, the thesis focuses on the appropriations in the music industry and includes the works of Lana Del Rey, Alizée, Melanie Martinez, Marilyn Manson, and Sia. The second main chapter focuses on the appropriation of Lolita in the sphere of advertising and thus focuses on various objects of promotion such as film posters, book covers, or Lolita becoming an inspiration for fragrances. The last chapter introduces the appropriations of Lolita in fashion industry with the focus on Western and non-Western perception of what a Lolita-inspired fashion means. In the individual analyses, the research focuses on the recurring themes or parts of the novel referenced in the appropriation. Moreover, the thesis also focuses on the popular nature of the chosen works and tries to observe what kind of impact their popularity has on the observer’s perception of the representation of the novel as well as the character of Lolita.