BABC011p Biochemistry and Haematology - lecture

Faculty of Medicine
Autumn 2017
Extent and Intensity
0/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. RNDr. Jiří Dostál, CSc. (lecturer)
MUDr. Michaela Králíková, Ph.D. (lecturer)
RNDr. Hana Paulová, CSc. (lecturer)
Mgr. Jiří Slanina, Ph.D. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
doc. RNDr. Josef Tomandl, Ph.D. (lecturer)
Mgr. Marie Tomandlová, Ph.D. (lecturer)
Guaranteed by
prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Biochemistry for bacherols follows secondary school chemistry and broadens the subject considerably to the level required for the study of successive subjects. After the completition of the subject student will understand physico-chemical processes important for biological systems, will know the structures and names biochemically important inorganic and organic compounds and explain their significance. Decribes the structure and properties of saccharides, lipids, steroids, amino acids, proteins, nucleotides and nucleic acids. Explains the metabolism of nutrients and its regulation.Understands how energy is generated, used, and stored by the various organs of the body.Describes the biochemical proceses typical for main organs and tissues in the body.
Syllabus
  • Basic terms. Solutions, concentrations. Electrolytes.osmotic pressure.
  • Protolytic reactions, acids, bases, pH, Hydrolysis of salts, buffers.
  • macrobiogenic and microbiogenic elements.Biochemically important inorganic compounds.
  • Organic compounds, hydrocarbonds and their deriatives.Alcohols, phenols, ethers. Carbonyl compounds. keton bodies.Carboxylic acids and their deivatives.Amines, heterocycles and their biochemically important derivatives.tnsides.
  • The chemistry of saccharides. Important monosaccharides and their derivatives.
  • Aminoacids, peptides, proteins.
  • Enzymes, structure, mechanism of action. Enzyme classification and nomenclature.Enzymes important in clinical biochemistry.
  • Lipids, phospholipids, glycolipids. Eicosanoids, steroids overview.Cholesterol.
  • Nucleosides and nucleotides, types of nucleic acids.replication, transcription.
  • Hemoproteins. Hem. Bile pigments.
  • General principles of metabolism. High-energy compounds. Citric acid cycle. Respiration chain, aerobic phosphorylation.
  • Saccharide metabolism, glycolysis, gluconeogenesis, synthesis of glycogen.
  • Metabolism of proteins and aminoacids. Proteins in food and their digestion. Intracellular degradation of proteins. Common features of amino acid degradation.Synthesis of urea.
  • Digestion and resorption of lipids. Fatty acid metabolism, ketogenesis. Cholesterol.
  • Characteristic features of metabolism at various conditions. metabolic aspects of diabetes.
  • Hormones, mechanism of their action. Neuron, neurotransmitters.
  • Biochemistry of liver.
  • Biochemistry of blood. Proteins in blood. Blood coagulation.
  • Water and ions in organism.
  • Biochemistry of kidneys.
  • Muscle proteins, molecular principles of contraction and relaxation.Smooth muscle. Biochemical markers of infarction.
  • Metabolism of xenobiotics.
  • Structure and metabolism of connective tissue.
  • Biochemistry of vision, rhodopsine cycle. Metabolism of the cornea and the lens.
Literature
Teaching methods
Teaching form are lectures. Lecture files are uploaded in advance in IS.
Assessment methods
Oral examination has 3 questions.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: celkem 10.
The course is also listed under the following terms Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/autumn2017/BABC011p