BLKLC011s Medical Chemistry seminar

Faculty of Medicine
autumn 2019
Extent and Intensity
0/0/0. 2 credit(s). Type of Completion: z (credit).
doc. RNDr. Jiří Dostál, CSc. (seminar tutor)
Mgr. Jana Gregorová, Ph.D. (seminar tutor)
MUDr. Miroslava Hlaváčová, Ph.D. (seminar tutor)
MUDr. Michaela Králíková, Ph.D. (seminar tutor)
RNDr. Hana Paulová, CSc. (seminar tutor)
Mgr. Ondřej Peš, Ph.D. (seminar tutor)
Mgr. Jiří Slanina, Ph.D. (seminar tutor)
prof. RNDr. Eva Táborská, CSc. (seminar tutor)
doc. RNDr. Josef Tomandl, Ph.D. (seminar tutor)
Mgr. Marie Tomandlová, Ph.D. (seminar tutor)
Lenka Nerudová (assistant)
Guaranteed by
prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry - Theoretical Departments - Faculty of Medicine
Contact Person: Lenka Nerudová
Supplier department: Department of Biochemistry - Theoretical Departments - Faculty of Medicine
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Seminars are complementary to Medical chemistry lecture (VSLC011p). The knowledge of general, inorganic, and (bio)organic chemistry, required in the end of VCLC011p, is thoroughly practiced during Medical chemistry seminars.
Learning outcomes
Students will be able to understand basics of general, inorganic and organic chemistry to the extent necessary for the further study of biochemistry.
They will be able to apply general physicochemical laws to processes in living organisms.
They will be able to describe the chemical properties of the most important biogenic elements and essential compounds of importance in medicine, nutrition and toxicology. They will be able to describe and discuss the properties and reactions of organic and bioorganic compounds important for the understanding of biochemical processes
  • The properties of single particles, mole and molar quantities. Concentration of solutions, basic laboratory calculations.
  • Test (Basic laboratory calculus.). Reaction kinetics, the law of chem. equilibrium.
  • Energy in chemical reactions, free energy and equilibrium, relationship between standard free energy change and equilibrium constant. English (and some Latin) names of inorganic compounds.
  • Dissociation of weak and strong electrolytes, activity of ions, ionic strength, osmolality.
  • Test (Reaction kinetics, thermodynamics of chemical changes, solutions of electrolytes; nomenclature of inorganic compounds).
  • Protolytic reactions, pH of acid, base, and salt solutions, buffers, calculations.
  • Oxidation-reduction, electrode potential, electrochemical cell potential and the free energy change.
  • Test (Acid-base reactions, oxidation and reduction).
  • Chemical properties of characteristic groups of carbon compounds, Part 1.
  • Chemical properties of characteristic groups of carbon compounds, Part 2.
  • Test (Organic compounds, nomenclature, structures, reactions). Heterocyclic compounds and their derivatives. Alkaloids.
  • Intermolecular forces and adsorption. Adsorption and liquid chromatography.
  • Chemistry of saccharides.
  • Test (Heterocycles, saccharides. Adsorption and chromatography). Chemistry of lipids and steroids.
  • Properties of amino acids. Proteins, secondary and tertiary structures.
  • Test (Summary).
    required literature
  • Podklady do seminářů v Informačním systému
Teaching methods
Class discussions based of materials in the seminar textbook.
Assessment methods
Conditions for giving the course-unit credit: First condition is full attendance in all lessons (or making up all missing and justified lessons). Five short tests are written during the semester. The total number of questions in all tests is 64, each correct answer is counted as one point. Students that will obtain 49 points or more during the semester are not obliged to write the credit test. The other students will write the credit test with the 30 questions in the last week of the semester. Students that will not fulfill this limit will be allowed to repeat the test once. Remedial dates for writing the credit test will be scheduled. Students that will not fulfill this requirement will not be given the course-unit credit. Obtaining of course-unit credits of practices and seminars is the pre-requisite for registration to the examination of Medical chemistry and for enrollment of Biochemistry in the Spring semester.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 10.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018.
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