LF:BZBC011p Biochemistry and Hematol.-lec. - Course Information

BZBC011p Biochemistry and Hematology - lecture

Extent and Intensity

2/0/0. 2 credit(s). Type of Completion: zk (examination).
Taught in person.

Teacher(s)

RNDr. Hana Paulová, CSc. (lecturer)
Mgr. Jiří Slanina, Ph.D. (lecturer)
doc. RNDr. Jiří Dostál, CSc. (assistant)
prof. RNDr. Eva Táborská, CSc. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant)
Mgr. Marie Tomandlová, Ph.D. (assistant)
MUDr. Michaela Králíková, Ph.D. (alternate examiner)

Guaranteed by

Mgr. Jiří Slanina, Ph.D.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Jiří Slanina, Ph.D.
Supplier department: Department of Biochemistry – Theoretical Departments – Faculty of Medicine

Prerequisites

Admission to the exam is conditional upon successful completion of the course BZBC011c

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• Paramedic practice (programme LF, B-ZACH)
• Paramedic (programme LF, B-SZ)

Course objectives

Biochemistry for bacherols follows secondary school chemistry and biochemistry broadens the subject considerably to the level required for the study of successive subjects. The aim of the subject is to provide a comprehensive view of the basic metabolic processes in the human body related to the functioning of the human organism. It gets information on the production and use of energy in the human body, the structure and synthesis of the main molecules, the main regulatory mechanisms that maintain homeostasis. Students will obtain knowledge about the biochemical nature of the most important disorders of metabolism and bases of their clinico-biochemical examination, taking into account their specialization.

Learning outcomes

After the completion of the subject students will understand physicochemical processes important for biological systems, He can explain the basic principles of nutrient metabolism and the principles of regulation. Understands how energy is generated, used, and stored by the various organs of the body. Describes the biochemical processes typical for main organs and tissues in the body (heart, liver, kidney muscle, nerve tissue). He can explain the basic principles of homeostasis. He is familiar with the effects of major hormones and the principle of their action through receptors. Characterizes the composition and function of the main body fluids. Understand the processes of hemocoagulation.

Syllabus

• Basic terms. Solutions, concentration. Electrolytes. Osmotic pressure. Acids and bases, pH. Buffers. • Biogenic elements – overview, significance. Toxic elements. • Biochemically important organic substances. • Surfactants. • Saccharides-properties, classifications, overview. • Amino acids, peptides, proteins – properties, classification, overview. • Enzymes-structures, mechanism of enzymatic action, overview. Enzymes important in clinical biochemistry. • Lipides- properties, classifications, overview. Steroids-overview. Cholesterol, bile pigments. • Vitamins. • Nucleosides and nucleotides, basic types of nucleic acids. • Replication, transcription, translation. • Membranes, transport. • Metabolismus of nutrients-overview. Production of energy in cells. • Digestion and resorption of saccharides. Metabolism of saccharides. • Proteins in food, digestion, resorption. Metabolism of proteins and amino acids. • Digestion and resorption of lipids. Lipoproteins. Metabolism of lipids. Metabolism of cholesterol. • Metabolism under different states. • Biochemistry of blood. • Degradation of blood pigment. • Management of water and ions in the body. • Acid-base balance in organism. • Biochemical function of liver, and kidneys. Muscle tissue biochemistry. Connective tissue biochemistry. • Signal molecules and receptors. • Nerve cell. Nerve signal transmission. • Biochemistry of vision. Basic biochemical examination, factors influencing the results. Biological material - blood and urine, its collection and processing. Hemoglobin, carbonylhemoglobin, methemoglobin – poisoning. Diabetes mellitus. Determination of glucosemia. Biochemical diagnosis of myocardial infarction. Proof of alcohol in breath and blood. Metabolism of ethanol. Orientation analyses of urine by diagnostic strips. Drug tests.

Literature

required literature
• PAULOVÁ, Hana. Biochemie pro nelékařské zdravotnické obory. 1. vydání. Brno: Masarykova univerzita, 2021, 154 stran. ISBN 9788021098589. info

Teaching methods

The course takes place in the form of lectures in the range 2 hours per week.

Assessment methods

PC test on computers in the computer room of the Department of Biochemistry. Detailed information on the exam is given in IS MUNI (Study materials-Organization instructions).

Language of instruction

Czech

Further comments (probably available only in Czech)

The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.

• Enrolment Statistics (autumn 2024, recent)
  
• Permalink: https://is.muni.cz/course/med/autumn2024/BZBC011p