DSNTz01 New trends in pathophysiology

Faculty of Medicine
autumn 2025
Extent and Intensity
0/0. 5 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
In-person direct teaching
Teacher(s)
prof. MUDr. Anna Vašků, CSc. (lecturer)
Bc. Lenka Hladíková (assistant)
Guaranteed by
prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Timetable
Fri 17. 10. 9:00–12:00 A18/205, Fri 7. 11. 9:00–12:00 A18/205, Fri 21. 11. 9:00–12:00 A18/205
Prerequisites
Lectures (3x4 hours) •Genetic ane epigenetic base of complex diseases • Molekular biology methods- their actual sense in diagnose and therapy of complex diseases • News in pathophysiology of complex diseases • Workshop (6 hrs in laboratories in case of interest - "Practical miminum from molecular biology".
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 230 fields of study the course is directly associated with, display
Abstract
The aim of the subject is furher confirmation and enhancement of pathophysiology knowledge, both at organ and molecular levels.
Learning outcomes
The student will be able to review results of basic genetic studies of complex diseases from the point of view of methodological and statistic evaluations. P> Student will confirm sontemporary knowledge of general and special pathophysiology (inflammation, microbiom, obesity, cancerogenesis, complex diseases) ;
The workshop will offer basic experience about practical performance of molecular biology methods (PCR, restriction analysis, electrophoretic presentation of genotypes, RT-PCR, sequencing)
Key topics
  • Lectures (3x4 hrs)
  • Genetic and epigenetic background of complex diseases (17. 10. 2025; 9:00-12:00, UCB,A18/205)
  • Molecular biological methods and their actual importance in clinical diagnostics and therapy (7. 11. 2025; 9:00-12:00, UCB, A18/205)
  • News in pathophysiology of complex diseases (21.11. 2025; 9:00-12:00, UCB, A18/205)
Study resources and literature
    recommended literature
  • DAMJANOV, Ivan. Pathophysiology. Illustrated by Matthew Chansky. 1st ed. Philadelphia: Saunders/Elsevier, 2009, vii, 464. ISBN 9781416002291. info
  • NEČAS, Emanuel. Obecná patologická fyziologie. 1. dotisk 2. vyd. Praha: Karolinum, 2007, 377 s. ISBN 9788024612911. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, s. 381-760. ISBN 9788024606743. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, 379 s. ISBN 9788024606750. info
Approaches, practices, and methods used in teaching
The education will be realized by lectures with continuous discussion with students.
Method of verifying learning outcomes and course completion requirements
Students will write an assay on the thema: Genetics and epigenetics in relation to my disertation thesis. The recherche results will be discussed during the oral examination.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
Information on completion of the course: Student vypracuje esej na téma Geny a téma mé disertační práce, nad níž se u zkoušky povede diskuse.
The course can also be completed outside the examination period.
The course is taught annually.
The course is also listed under the following terms Spring 2000, Autumn 2001, Spring 2002, Autumn 2002, Spring 2003, Autumn 2003, Spring 2004, Autumn 2004, Spring 2005, Autumn 2005, Spring 2006, Autumn 2006, Spring 2007, Autumn 2007, Spring 2008, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (recent)
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