EMEM0933s Embryology III - seminar

Faculty of Medicine
autumn 2025
Extent and Intensity
2/0/0. 6 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. MVDr. Aleš Hampl, CSc. (lecturer)
PharmDr. Zuzana Holubcová, Ph.D. (lecturer)
Mgr. Kristína Valovičová (lecturer)
MUDr. Eva Mecová (seminar tutor)
Guaranteed by
doc. MVDr. Aleš Hampl, CSc.
Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Contact Person: PharmDr. Zuzana Holubcová, Ph.D.
Supplier department: Department of Histology and Embryology – Theoretical Departments – Faculty of Medicine
Timetable
Wed 16:00–17:40 F01B1/126
Prerequisites
EMEM0832p Embryology II - lecture
EMEM0832p
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of this course is for students to gain a thorough understanding of the biology of peri- and post-implantation development, fetal development, including factors influencing the course of pregnancy, labour, and lactation.
Learning outcomes
Graduates of the course will: • - have detailed knowledge of the process of implantation and post-implantation development • - have a comprehensive overview of the course of pregnancy and possible complications of gestation and delivery • - have awareness of reproductive differences between humans and other animal species
Syllabus
• -embryonic hatching, development of multiple pregnancy, endocrine and paracrine signaling during implantation, embryo–endometrium interactions • -hormonal regulation of the menstrual cycle, cyclic changes of the endometrium, decidualization and vascularization, implantation window, endometrial receptivity, uterine microbiome, menstrual disorders, endometriosis • -stages of implantation, trophoblast invasion, role of immunological tolerance, implantation failure, and early pregnancy loss • -pathologies of implantation – ectopic pregnancy, development and function of the placenta, trophoblastic disease, molar pregnancy • -chimerism and microchimerism, risk factors of the first trimester • -gastrulation, differentiation of the three germ layers, overview of organogenesis, causes of miscarriage • -experimental models of peri- and post-implantation development, ex utero organogenesis • -pregnancy complications – preeclampsia, HELLP syndrome, thrombotic complications of pregnancy, gestational diabetes, fetal growth restriction, diagnosis of congenital malformations • -clinical reproductive immunology – significance, diagnostic methods, impact of autoimmune diseases on fertility • -reproductive endocrinology – influence of endocrine disorders on fertility and the course of pregnancy • - physiological childbirth and obstetric complications • - molecular mechanisms and (patho)physiology of lactation • - pharmacologically induced infertility and the impact of patient medication on IVF success • -interspecies reproductive differences, application of assisted reproduction techniques in veterinary medicine
Literature
    recommended literature
  • Dekner HW, Aplin J: Trofoblast Invasion and Endomerial Receptivity. 1st ed. New York 1990.
  • Critchley H, Cameron I, Smith S: Implantation and Early Development. 1st ed. London 2005.
Teaching methods
seminars The condition for admission to the exam is participation in lectures by external lecturers
Assessment methods
written exam
Language of instruction
Czech
Follow-Up Courses
Further Comments
Study Materials
Listed among pre-requisites of other courses
The course is also listed under the following terms autumn 2024.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/med/autumn2025/EMEM0933s