ZLBI0121p Biology I - lecture

Faculty of Medicine
Autumn 2008
Extent and Intensity
1/0. 0 credit(s). Type of Completion: -.
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. MVDr. Aleš Hampl, CSc. (lecturer)
prof. MUDr. Marie Kopecká, CSc. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Hana Hříbková, Ph.D. (assistant)
Mgr. Vítězslav Kříž, Ph.D. (assistant)
Debora Ledahudcová (assistant)
Mgr. Petra Pospíšilová, Ph.D. (assistant)
Ing. Lucia Ráheľová (assistant)
prof. MUDr. Iva Slaninová, Ph.D. (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Debora Ledahudcová
Timetable
each odd Wednesday 7:00–8:50 KOM 200
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course provides an overview of the current knowledge of molecular biology and cell biology in the context of other theoretical branches of the Faculty of Medicine. Recent and modern concepts of molecular cell structures, functional organization of the cell and gene expression and regulation are presented to students. As an extension of these topics, a molecular mechanism of gametogenesis and fertilization as well as cell division and cell cycle are discussed. In addition, a short introduction to genomics and analyses of the human genome is included. The subject matter presented in this course will help to better understand other subjects including physiology, pathology and human and clinical genetics.
Syllabus
  • 1st WEEK: Lecture: Structural biology and basic functions of the prokaryotic and eukaryotic cell (Prof. MUDr. Augustin Svoboda, CSc.) 2nd WEEK: Lecture: Structure and function of the cell membrane. Mechanisms of cellular adhesion and migration (prof. MUDr. Augustin Svoboda, CSc.) 3rd WEEK: Lecture: Organelles and mechanisms maintaining their topology (prof. MUDr. Augustin Svoboda, CSc.) 4th WEEK: Lecture: Structure and dynamics of the nucleus. Topology of nuclear processes (prof. MUDr. Augustin Svoboda, CSc) 5th WEEK: Lecture: Cytoskeleton (Doc. MUDr. Marie Kopecká, CSc.) 6th WEEK: Lecture: From genotype to phenotype - introduction to molecular genetics (Doc. MUDr. David Šmajs, Ph.D.) 7th WEEK: Lecture: Molecular mechanisms regulating protein expression (Doc. MVDr. Aleš Hampl, CSc.) 8th WEEK: Lecture: Molecular mechanisms regulating cell cycle and cell proliferation; macromolecular interactions in model systems (Doc. MVDr. Aleš Hampl, CSc.) 9th WEEK: Lecture: Molecular mechanisms of gametogenesis and fertilization - theory and applications (Doc. MVDr. Aleš Hampl, CSc ) 10th WEEK: Lecture: Mitosis and cytokinesis (Doc. MUDr. Marie Kopecká,CSc.) 11th WEEK: Lecture: DNA polymorphisms, mutations and genetically determined diseases (Doc. MUDr. Marie Kopecká,CSc.) 12th WEEK: Lecture: Regulation of gene expression – principles and examples(Doc. MUDr. David Šmajs, Ph.D.) 13th WEEK: Lecture: Comparative and functional genomics (Doc. MUDr. David Šmajs, Ph.D.) 14th WEEK: Lecture: Human genome, human genome project and postgenomic era (Doc. MUDr. David Šmajs, Ph.D.)
Literature
  • Snustad D. Peter, Simmons Michael D.: Genetika (1.české vydání, přeloženo z Principles of Genetics), Nakladatelství Masarykovy univerzity 2009, 864 stran.
  • Snustad D. Peter, Simmons Michael D.: Principles of Genetics, 5th edition, Wiley&Sons, 2009.
  • Campbell, N., A., Reece, J., B. 2006.Biologie. Computer press (ISBN: 80-251-1178-4)
  • Alberts, B., et al..: Základy buněčné biologie: úvod do molekulární biologie buňky. Espero Publishing, Ústí nad Labem 2005, 740, ISBN-10: 80-902906-2-0
  • Lodish, H., Berk, A., Matsudaira, P., Kaiser,C.A., Krieger, M., Scott, M.P., Zipurski, L., Darnell, J.: Molecular Cell Biology 5th ed., 2004 (ISBN: 0-7167-4366-3)
  • Pollard, Thomas D., Earnshaw, William C.: Cell Biology, 2nd ed., Saunders-Elsevier, Philadelphia, 2008
Assessment methods
written examination, lecture attendance is optional
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Teacher's information
http://www.med.muni.cz/toCP1250.cs/biologie/frame_cz.html
The course is also listed under the following terms Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2008, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2008/ZLBI0121p