VSPF0521p Pathological Physiology - lectures

Faculty of Medicine
Autumn 2009
Extent and Intensity
2/0/0. 1 credit(s). Recommended Type of Completion: RZk (examination). Other types of completion: -.
Teacher(s)
prof. MUDr. Anna Vašků, CSc. (lecturer)
prof. MUDr. Lydie Izakovičová Hollá, Ph.D. (lecturer)
prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer)
Věra Ježková (assistant)
Guaranteed by
prof. MUDr. Anna Vašků, CSc.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Contact Person: prof. MUDr. Anna Vašků, CSc.
Timetable
Mon 28. 9. to Fri 8. 1. Wed 13:30–15:10 P31 Posluchárna A. I. Bláhy
Prerequisites (in Czech)
VSFY0422p Physiology II - lecture && ( VSBC041p Biochemistry II -l || VSBC0422p Biochemistry II -l ) && VSAN0333p Anatomy III l && VSHE0322p Histology and embryology II -l && ( VSLT0221s Bas. Med. Terminol. II -s || VSLT011s Bas. Med. Terminology -l ) && VSET021 Medical Ethics I
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the subject is to teach students to be able to answer a sufficient number of pathophysiologically asked questions "why", especially focused on these themes:
Pathological Physiology as a science. Disease, health, normality. Descriptivism contra normativism.
Physiology of genes, regulation of gene activity.
Monogenic and multigenic diseases.
Shock syndrome.
Reactive oxygen species (ROS). Ionising radiation effects on cellular level.
Ionising radiation effects on tissue and organismal level.
Cardiovascular pathophysiology - systolic and diastolic function.
Cardiac failure.
Myocardial ischemia.
Hypertension.
Pathophysiology of the gas exchange in the lungs.
Pathophysiology of respiratory mechanics.
Chronic obstructive bronchopulmonary disease.
Restriction pulmonary diseases, respiratory failure.
Physiology of membrane transports.
Syllabus
  • 22/9 2009 Pathophysiology: an integrating medical speciality. Aetiology and pathogenesis of diseases.
  • Lecturer: Prof. Vašků
  • 29/9 Inflammation. Acute phase reaction. Cytokines network. Chemokines.
  • Prof.Vašků
  • 6/10 Regeneration. Wound healing.
  • Assoc. prof. Kaňková
  • 13/10 Lipids.
  • Assoc. prof. Kaňková
  • 20/10 Volume and pressure overload; systolic and diastolic dysfunction of the heart. Shock and heart failure.
  • Prof. Vašků
  • 27/10 Ischemic heart disease, myocardial infarction, arrhythmias. Pathogenesis and selected clinical aspects.
  • Assoc. Prof. Kaňková
  • 3/11 Metabolism of myocardium and blood vessels and their remodelling in pathophysiological states. Peripheral blood vessels diseases.
  • Prof. Vašků
  • 10/11 General adaptation syndrome.
  • Prof. Vašků
  • 17/11 Bank Holiday
  • 24/11 Pathophysiology of gas exchange in the lungs. Ventilation control.
  • Prof. Vašků
  • 1/12 Lung diseases.
  • Prof. Izakovičová Hollá
  • 8/12 Kidney as a regulatory organ. Kidney perfusion regulation.
  • Prof. Vašků
  • 15/12 Acute and chronic renal failure.
  • Prof. Izakovičová Hollá
  • 5/1 2010 Glomerular and tubular disease.
  • Prof. Izakovičová Hollá
Literature
  • NEČAS, Emanuel a spol. Obecná patologická fyziologie. 1. vyd. Praha: Karolinum, 2000, 377 pp. ISBN 80-246-0051-X. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, 379 s. ISBN 9788024606750. info
  • NEČAS, Emanuel. Patologická fyziologie orgánových systémů. 1. vyd. Praha: Karolinum, 2003, s. 381-760. ISBN 9788024606743. info
  • PORTH, Carol. Pathophysiology : concepts of altered health states. 5th ed. Philadelphia: Lippincott-Raven, 1998, xxviii, 14. ISBN 0397554133. info
Teaching methods
lecture
Assessment methods
The attendance of lectures and only one absence on practicals per semester are necessary for succesfull accomplishment of the subject. Continous control of knowlledge in practicals is fully in powers of teachers (assays, tests...). Elaborated proceedings of practicals will be put to teachers for credit.
Language of instruction
Czech
Further Comments
The course is taught annually.
The course is also listed under the following terms Autumn 2000, Autumn 2001, Autumn 2002, Autumn 2003, Autumn 2004, Autumn 2005, Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017.
  • Enrolment Statistics (Autumn 2009, recent)
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