MBLG071c Medical genetics - practices

Faculty of Medicine
autumn 2021
Extent and Intensity
0/1/0. 1 credit(s). Type of Completion: z (credit).
Teacher(s)
RNDr. Iveta Valášková, Ph.D. (seminar tutor)
Mgr. Marta Navaříková (seminar tutor)
Renata Spěšná (seminar tutor)
Bc. Kateřina Stehlíková, DiS. (assistant)
Guaranteed by
RNDr. Iveta Valášková, Ph.D.
Institute of Medical Genetics and Genomics – Institutions shared with the Faculty Hospital Brno (paediatric medicine) – Faculty of Medicine
Contact Person: Bc. Kateřina Stehlíková, DiS.
Supplier department: Institute of Medical Genetics and Genomics – Institutions shared with the Faculty Hospital Brno (paediatric medicine) – Faculty of Medicine
Timetable
Wed 15. 9. 12:30–15:00 ÚP P01014, Fri 1. 10. 9:00–11:30 ÚLGG N03049, Fri 15. 10. 9:00–11:30 F01B1/635, Fri 29. 10. 9:00–11:30 F01B1/635, Fri 12. 11. 9:00–11:30 F01B1/635
Prerequisites
completed undergraduate studies (disciplines: biology, molecular biology, biochemistry etc.)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course acquaints students with basic knowledge in the field of clinical genetics. The aim is to get a basic overview of clinical genetics, to learn the basic rules of inheritance of signs and diseases, to outline the basics of applied genetics in medicine. To get a basic overview of clinical cytogenetics and molecular cytogenetics. To obtain a basic overview of DNA diagnostics of serious inherited diseases.
Learning outcomes
Upon completion of the course the student will be able to join the laboratory teams of clinical genetics. The acquired knowledge and practical skills will be able to apply in the laboratory procedures in cytogenetics and molecular cytogenetics, including DNA analysis techniques.
Syllabus
  • Preparation and evaluation of cytogenetic preparations for prenatal cytogenetic diagnostics, chorionic treatment, amniotic fluid. Preparation and evaluation of preparations for postnatal cytogenetic diagnosis - peripheral and fetal blood lymphocytes. The use of molecular cytogenetic methods in clinical cytogenetics (FISH, M-FISH, array-CGH) Long-term cultivation for cytogenetic examination. Isolation, processing and storage of DNA / RNA in the diagnosis of hereditary diseases. Direct and indirect DNA analysis. PCR, electrophoresis, screening methods in DNA diagnostics, fragmentation analysis, sequencing of human DNA in the diagnosis of hereditary diseases. Use of DNA analysis in the prenatal diagnosis of serious hereditary diseases.
Literature
  • Dopl.
Teaching methods
Performance, writing and evaluation of the laboratory task. Consulation of findings with the teacher
Assessment methods
Credits are granted for active participation, attendance and writing of quality protocols of individual tasks.
Language of instruction
Czech
Further comments (probably available only in Czech)
Information on the extent and intensity of the course: 15.
The course is also listed under the following terms Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (autumn 2021, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2021/MBLG071c