BLKG051x Clinical Genetics - practice

Faculty of Medicine
autumn 2025
Extent and Intensity
0/0/0. 5 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
MUDr. Renata Gaillyová, Ph.D. (lecturer)
prof. MUDr. Michael Doubek, Ph.D. (seminar tutor)
MVDr. Petra Šmuhařová (seminar tutor)
RNDr. Iveta Valášková, Ph.D. (seminar tutor)
Bc. Kateřina Stehlíková, DiS. (assistant)
Guaranteed by
RNDr. Iveta Valášková, Ph.D.
Institute of Medical Genetics and Genomics – Institutions shared with the Faculty Hospital Brno (paediatric medicine) – Faculty of Medicine
Contact Person: Bc. Kateřina Stehlíková, DiS.
Supplier department: Institute of Medical Genetics and Genomics – Institutions shared with the Faculty Hospital Brno (paediatric medicine) – Faculty of Medicine
Timetable of Seminar Groups
BLKG051x/1: Wed 29. 10. 8:00–10:30 ÚLGG N03049, 12:00–14:50 ÚLGG N04022, Thu 30. 10. 8:00–13:50 ÚLGG N03049, Fri 31. 10. 8:00–13:50 ÚLGG N03049, Tue 4. 11. 8:00–13:00 ÚLGG N03049, Wed 5. 11. 8:00–13:00 ÚLGG N03049, Thu 6. 11. 8:00–13:00 ÚLGG N03049, Fri 7. 11. 8:00–13:00 ÚLGG N03049
BLKG051x/2: No timetable has been entered into IS.
BLKG051x/3: Tue 16. 9. 8:00–13:50 ÚLGG N03049, Wed 17. 9. 8:00–10:30 ÚLGG N03049, 12:00–14:50 ÚLGG N04022, Thu 18. 9. 8:00–13:50 ÚLGG N03049, Fri 19. 9. 8:00–13:50 ÚLGG N03049, Tue 23. 9. 8:00–13:00 ÚLGG N03049, Wed 24. 9. 8:00–13:00 ÚLGG N03049, Thu 25. 9. 8:00–13:00 ÚLGG N03049, Fri 26. 9. 8:00–13:00 ÚLGG N03049
BLKG051x/4: Tue 14. 10. 8:00–13:50 ÚLGG N03049, Wed 15. 10. 8:00–10:30 ÚLGG N03049, 12:00–14:50 ÚLGG N04022, Thu 16. 10. 8:00–13:50 ÚLGG N03049, Fri 17. 10. 8:00–13:50 ÚLGG N03049, Tue 21. 10. 8:00–13:00 ÚLGG N03049, Wed 22. 10. 8:00–13:00 ÚLGG N03049, Thu 23. 10. 8:00–13:00 ÚLGG N03049, Fri 24. 10. 8:00–13:00 ÚLGG N03049
BLKG051x/5: Tue 25. 11. 8:00–13:50 ÚLGG N03049, Wed 26. 11. 8:00–10:30 ÚLGG N03049, 12:00–14:50 ÚLGG N04022, Thu 27. 11. 8:00–13:50 ÚLGG N03049, Fri 28. 11. 8:00–13:50 ÚLGG N03049, Tue 2. 12. 8:00–13:00 ÚLGG N03049, Wed 3. 12. 8:00–13:00 ÚLGG N03049, Thu 4. 12. 8:00–13:00 ÚLGG N03049, Fri 5. 12. 8:00–13:00 ÚLGG N03049
BLKG051x/6: Tue 30. 9. 8:00–13:50 ÚLGG N03049, Wed 1. 10. 8:00–10:30 ÚLGG N03049, 12:00–14:50 ÚLGG N04022, Thu 2. 10. 8:00–13:50 ÚLGG N03049, Fri 3. 10. 8:00–13:50 ÚLGG N03049, Tue 7. 10. 8:00–13:00 ÚLGG N03049, Wed 8. 10. 8:00–13:00 ÚLGG N03049, Thu 9. 10. 8:00–13:00 ÚLGG N03049, Fri 10. 10. 8:00–13:00 ÚLGG N03049
BLKG051x/7: Tue 9. 12. 8:00–13:50 ÚLGG N03049, Wed 10. 12. 8:00–13:50 ÚLGG N03049, Thu 11. 12. 8:00–13:50 ÚLGG N03049, Fri 12. 12. 8:00–13:50 ÚLGG N03049, Tue 16. 12. 8:00–13:50 ÚLGG N03049, Wed 17. 12. 8:00–13:50 ÚLGG N03049, Thu 18. 12. 8:00–13:50 ÚLGG N03049, Fri 19. 12. 8:00–13:50 ÚLGG N03049
Prerequisites
BLKG0311 Clinical Genetics
Clinical Genetics - lectures
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Specialist practice complements the practical part of education in Clinical Biochemistry, Clinical Hematology, Immunohematology and Transfusion medicine, Clinical Microbiology, Clinical Immunology, Clinical Genetics and Pathologic Anatomy – Histopathologic determination methods. Students become familiar with the organization of workflow processes and basic documentation of laboratory worksites and will perform select tasks and activities.; The aim of the course is to acquaint students with the operation in genetic laboratories, laboratory equipment and instrumentation procedures. Part of the course is get basic knowledge about genetic testing procedures.
Learning outcomes
student knows the basic concepts and diagnosis in medical genetics student will be able - to clarify the type of inheritance - to determine biological materiál for genetic tests - to propose a testing method for genetic analysis
Syllabus
Methods of classical cytogenetics Making preparations for the analysis of congenital and acquired chromosomal aberrations up. Evaluation of chromosomal preparations under the light microscope and by computer image analysis. Methods of Molecular Cytogenetics. Method of fluorescence in situ hybridization, evaluation of preparations in the fluorescent microscope. Showing results of metaphases and interphase FISH. Methods SKY, array-CGH. Methods of Molecular Genetics. Taking of peripheral blood, DNA isolation methods, quality control of DNA, RNA isolation. PCR amplification method. Detection of PCR products, electrophoresis in polyacrylamide gel. Methods of detection of mutations in clinical genetics (DGGE, SSCP, Real time PCR, fragmentation analysis, sequencing, NGS).
Literature
  • DASTYCH, Milan. Instrumentální technika : obor zdravotní laborant. 2., dopl. vyd. Brno: Masarykova univerzita, 2014, 201 s. ISBN 9788021071032. info
  • DASTYCH, Milan; Ludmila BOURKOVÁ; Marta HANÁKOVÁ; Jana JURÁNKOVÁ; Eva TESAŘOVÁ; Iveta VALÁŠKOVÁ and Jiřina ZAVŘELOVÁ. Instrumentální technika. Obor zdravotní laborant. 1. vyd. Brno: Masarykova univerzita, 2014. ISBN 978-80-210-7103-2. info
Teaching methods
trainee - ship
Assessment methods
confirmation of completion of practice
Language of instruction
Czech
The course is also listed under the following terms Autumn 2007, Autumn 2008, Spring 2009, Autumn 2009, Spring 2010, Autumn 2010, Spring 2011, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (recent)
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