APFYp Pathological physiology - lecture

Faculty of Medicine
spring 2025
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
MUDr. Vendula Bartáková, Ph.D. (lecturer)
doc. MUDr. Jaromír Gumulec, Ph.D. (lecturer)
MUDr. Michal Jurajda, Ph.D. (lecturer)
Mgr. Andrea Knight, Ph.D. (lecturer)
prof. RNDr. Michal Masařík, Ph.D. (lecturer)
Mgr. Lukáš Pácal, Ph.D. (lecturer)
Dipl. Ing. Martin Piskáček, Dr. rer. nat. (lecturer)
doc. RNDr. Sabina Ševčíková, Ph.D. (lecturer)
prof. MUDr. Anna Vašků, CSc. (lecturer)
Bc. Lenka Hladíková (assistant)
Guaranteed by
MUDr. Michal Jurajda, Ph.D.
Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Supplier department: Department of Pathophysiology – Theoretical Departments – Faculty of Medicine
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completing this course the students are able to explain basic etiopathogenesis of diseases (physical, chemical and biological including genetic) and their consequences. The outcome of the education is to induce ability to understand logic base of clinical manifestation of diseases using both analytical ans synthetical approaches.
Syllabus
  • 1. Healthy and disease. Etiology and pathogenesis. Stress.
  • 2. Inflammation. Cell and cellular interactions in pathogenesis of tissue damage. Acute phase reaction.
  • 3. Wound healing. Malignant transformation.
  • 4. Disturbances of immune system- immunodeficiency, hypersensitivity, autoimmunity in disease pathogenesis.
  • 5. Basic genetics-monogenic vs. complex diseases.
  • 6. Pathophysiology of blood forming tissue.
  • 7. Disturbances of volume and tonicity of body fluids. Disturbances of internal homeostasis.
  • 8. Pathophysiology of cardiovascular system I.
  • 9. Pathophysiology of cardiovascular system II.
  • 10. Pathophysiology of respiratory system.
  • 11. Pathophysiology of urogenital system.
  • 12. Pathophysiology of digestive system.
  • 13. Pathophysiology of hormones.
  • 14. Pathophysiology of nervous and muscular systems.
Literature
  • KAŇKOVÁ, Kateřina, Dobroslav HÁJEK, Marcel HORKÝ, Lydie IZAKOVIČOVÁ HOLLÁ, Michal JURAJDA, Vladimír KOTALA, Jiří VÁCHA, Anna VAŠKŮ and Vladimír ZNOJIL. Patologická fyziologie pro bakalářské studijní programy (Pathophysiology for paramedical study programms). 1st ed. Brno: Masarykova univerzita v Brně, 2003, 161 pp. 1. vydání. ISBN 80-210-3112-3. info
  • HALL, John E. Pocket companion to Guyton & Hall textbook of medical physiology. 11th ed. Philadelphia: Saunders Elsevier, 2006, xviii, 709. ISBN 1416002138. info
Teaching methods
lectures with discussion
Assessment methods
Written test followed by oral exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: every week.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.
  • Enrolment Statistics (spring 2025, recent)
  • Permalink: https://is.muni.cz/course/med/spring2025/APFYp